In: Cerebral Cortex, 2018, p. -
The axonal composition of cortical projections originating in premotor, supplementary motor (SMA), primary motor (a4), somatosensory and parietal areas and descending towards the brain stem and spinal cord was characterized in the monkey with histological tract tracing, electron microscopy (EM) and diffusion MRI (dMRI). These 3 approaches provided complementary information. Histology provided...
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In: Clinical Infectious Diseases, 2018, vol. 66, no. 8, p. 1290–1297
The dramatic increase in the prevalence and clinical impact of infections caused by bacteria producing carbapenemases is a global health concern. Carbapenemase production is especially problematic when encountered in members of the family Enterobacteriaceae. Due to their ability to readily spread and colonize patients in healthcare environments, preventing the transmission of these organisms...
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In: European Journal of Clinical Nutrition, 2018, vol. 72, no. 5, p. 665–679
Although Switzerland is considered a small country, it has its share in discoveries, inventions and developments for the assessment of energy metabolism. This includes seminal contributions to respiratory and metabolic physiology and to devices for measuring energy expenditure by direct and indirect calorimetry in vivo in humans and small animals (as well as in vitro in organs/tissues), for...
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In: Journal of Chromatography B, 2018, vol. 1081–1082, p. 101–108
The plasma of Parkinson's disease (PD) patients may contain various altered metabolites associated with the risk or progression of the disease. Characterization of the abnormal metabolic pattern in PD plasma is therefore critical for the search for potential PD biomarkers. We collected blood plasma samples from PD patients and used an LC-MS based metabolomics approach to identify 17...
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In: Cell and Tissue Research, 2018, vol. 372, no. 2, p. 163–170
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In: Advances in Nutrition, 2018, vol. 9, no. 2, p. 70–77
Cardiovascular diseases are still the primary cause of mortality worldwide, with high blood pressure and type 2 diabetes as major promoters. Over the past 3 decades, almost in parallel with the rise in cardiovascular disease incidence, the consumption of sugar-sweetened beverages (SSBs) has increased. In this context, SSBs are potential contributors to weight gain and increase the risk for...
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In: European Journal of Clinical Nutrition, 2018, vol. 72, no. 5, p. 657–664
Collateral fattening refers to the process whereby excess fat is deposited as a result of the body’s attempt to counter a deficit in lean mass through overeating. Its demonstration and significance to weight regulation and obesity can be traced to work on energy budget strategies in growing mammals and birds, and to men recovering from experimental starvation. The cardinal features of...
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In: PLOS ONE, 2018, vol. 13, no. 4, p. e0195781
We investigated how visual and kinaesthetic/efferent information is integrated for speed perception in running. Twelve moderately trained to trained subjects ran on a treadmill at three different speeds (8, 10, 12 km/h) in front of a moving virtual scene. They were asked to match the visual speed of the scene to their running speed–i.e., treadmill’s speed. For each trial, participants...
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In: Oncotarget, 2018, vol. 9, no. 5, p. -
Novel adjuvants are needed to increase the efficacy of vaccine formulations and immune therapies for cancer and chronic infections. In particular, adjuvants that promote a strong type I IFN response are required, since this cytokine is crucial for the development of efficient anti-tumoral and anti-viral immunity. Nucleic acid band 2 (NAB2) is a double- stranded RNA molecule isolated from...
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In: Geometry & Topology, 2017, vol. 22, no. 1, p. 591–644
We study the intrinsic structure of parametric minimal discs in metric spaces admitting a quadratic isoperimetric inequality. We associate to each minimal disc a compact, geodesic metric space whose geometric, topological, and analytic properties are controlled by the isoperimetric inequality. Its geometry can be used to control the shapes of all curves and therefore the geometry and topology...
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