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Benchmarking smartphone fluorescence-based microscopy with DNA origami nanobeads: reducing the gap toward single-molecule sensitivity

Vietz, Carolin ; Schütte, Max L. ; Wei, Qingshan ; Richter, Lars ; Lalkens, Birka ; Aydogan Ozcan ; Tinnefeld, Philip ; Acuna, Guillermo P.

In: ACS Omega, 2019, vol. 4, no. 1, p. 637–642

Smartphone-based fluorescence microscopy has been rapidly developing over the last few years, enabling point-of-need detection of cells, bacteria, viruses, and biomarkers. These mobile microscopy devices are cost-effective, field-portable, and easy to use, and benefit from economies of scale. Recent developments in smartphone camera technology have improved their performance, getting closer...