Affiner les résultats

Protein phosphatases and their potential implications in neuroprotective processes

Gee, C. ; Mansuy, I.

In: Cellular and Molecular Life Sciences CMLS, 2005, vol. 62, no. 10, p. 1120-1130

Molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function

Savaskan, Nicolai E. ; Ufer, Christoph ; Kühn, Hartmut ; Borchert, Astrid

In: Biological Chemistry, 2007, vol. 388, no. 10, p. 1007-1017

Ectopic parvalbumin expression in mouse forebrain neurons increases excitotoxic injury provoked by ibotenic acid injection into the striatum

Maetzler, Walter ; Bendfeldt, Kerstin ; Racay, Peter ; Vollenweider, Florence ; Schwaller, Beat

In: Experimental Neurology, 2004, vol. 186, no. 1, p. 78-88

A neuroprotective role for Ca²⁺-binding proteins in neurodegenerative conditions ranging from ischemia to Alzheimer's disease has been suggested in several studies. A key phenomenon in neurodegeneration is the Ca²⁺-mediated excitotoxicity brought about by the neurotransmitter glutamate. To evaluate the relative ability to resist excitotoxicity of neurons containing the slow-onset...