Université de Fribourg

Functional metathesis catalyst through ring closing enyne metathesis: one pot protocol for living heterotelechelic polymers

Pal, Subhajit ; Lucarini, Fiorella ; Ruggi, Albert ; Kilbinger, Andreas F. M.

In: Journal of the American Chemical Society, 2018, vol. 140, no. 9, p. 3181–3185

Enyne ring closing metathesis has been used to synthesize functional group carrying metathesis catalysts from a commercial (Ru-benzylidene) Grubbs’ catalysts. The new Grubbs-type ruthenium carbene was used to synthesize living heterotelechelic ROMP polymers without any intermediate purification. Olefin metathesis with a mono substituted alkyne followed by ring closing metathesis with an...

Université de Fribourg

Cis- and trans-9,10-di(1H-imidazol-1-yl)-anthracene based coordination polymers of ZnII and CdII: synthesis, crystal structures and luminescence properties

Vasylevskyi, Serhii I. ; Regeta, Khrystyna ; Ruggi, Albert ; Petoud, Stéphane ; Piguet, Claude ; Fromm, Katharina M.

In: Dalton Transactions, 2018, vol. 47, no. 2, p. 596–607

New functional coordination polymers based on the semi-flexible 9,10-di(1H-imidazol- 1-yl)-anthracene ligand (L) with ZnII and CdII, namely {[Zn(μ2-L)2] (ClO4)2·m(MeOH)·n(DCM)}n (1), {[Zn(μ2-L)2](BF4)2·m(MeOH)·n(DCM)}n (2), {[Zn(μ2-L)2(p-Tos)2]·m(DCM)·n(MeOH)}n (3), {[Cd(μ2-L)2(p-Tos)2]·m(DCM)}n (4) {[Cd(μ2-L)2(p-Tos)2]·m(MeOH)·n(Dioxane)}n (5) and {[Zn(μ2-...

Université de Fribourg

Synthesis of hydrophilic and hydrophobic carbon quantum dots from waste of wine fermentation

Varisco, Massimo ; Zufferey, Denis ; Ruggi, Albert ; Zhang, Yucheng ; Erni, Rolf ; Mamula, Olimpia

In: Royal Society Open Science, 2017, vol. 4, no. 12, p. 170900

Wine lees are one of the main residues formed in vast quantities during the fermentation of wine. While toxic when applied to plants and wetlands, it is a biodegradable material, and several alternatives have been proposed for its valorization as: dietary supplement in animal feed, source for various yeast extracts and bioconversion feedstock. The implementation of stricter environment...

Université de Fribourg

Heterotelechelic polymers by ring‐opening metathesis and regioselective chain transfer

Yasir, Peng Liu, Mohammad ; Ruggi, Albert ; Kilbinger, Andreas F. M.

In: Angewandte Chemie International Edition, 2018, vol. 57, no. 4, p. 914–917

Heterotelechelic polymers were synthesized by a kinetic telechelic ring-opening metathesis polymerization method relying on the regioselective cross-metathesis of the propagating Grubbs’ first-generation catalyst with cinnamyl alcohol derivatives. This procedure allowed the synthesis of hetero-bis-end-functional polymers in a one- pot setup. The molecular weight of the polymers could be...

Université de Fribourg

Heptacoordinate Coii complex: a new architecture for photochemical hydrogen production

Lucarini, Fiorella ; Pastore, Mariachiara ; Vasylevskyi, Serhii ; Varisco, Massimo ; Solari, Euro ; Crochet, Aurelien ; Fromm, Katharina M. ; Zobi, Fabio ; Ruggi, Albert

In: Chemistry - A European Journal, 2017, p. -

The first heptacoordinate cobalt catalyst for light-driven hydrogen production in water has been synthesized and characterized. Photochemical experiments using [Ru(bpy)₃]²⁺ as photosensitizer gave a turnover number (TON) of 16300 mol H₂ (mol cat.)⁻¹ achieved in 2 hours of irradiation with visible (475 nm) light. This promising result provides a path forward in the...

Université de Fribourg

Red-light activated photoCORMs of Mn(I) species bearing electron deficient 2,2′-azopyridines

Kottelat, Emmanuel ; Ruggi, Albert ; Zobi, Fabio

In: Dalton Transactions, 2016, vol. 45, no. 16, p. 6920–6927

The realization of CO releasing molecules triggered by light (photoCORMs) within the phototherapeutic window (λ > 600 nm) constitutes an important goal for potential therapeutic applications of the molecules. The activation of photoCORMs with red/NIR light would enable exploiting the higher depth of penetration of this radiation with respect to higher energy photons. In this article we...

Université de Fribourg

Quantum-CORMs: quantum dot sensitized CO releasing molecules

Ruggi, Albert ; Zobi, Fabio

In: Dalton Transactions, 2015, vol. 44, no. 24, p. 10928–10931

The synthesis and photodecomposition behaviour of a family of CO releasing molecules (CORMs) based on [Mn(CO)₃bpy] derivatives connected to a semiconductor Quantum Dot (QD) sensitizer is described here. Compared to the non-sensitized complexes, such systems show a 2 to 6-fold increase of the photodecomposition rate upon irradiation with visible light.

Université de Fribourg

Synthesis, characterization and cellular location of cytotoxic constitutional organometallic isomers of rhenium delivered on a cyanocobalmin scaffold

Santoro, Giuseppe ; Zlateva, Theodora ; Ruggi, Albert ; Quaroni, Luca ; Zobi, Fabio

In: Dalton Transactions, 2015, vol. 44, no. 15, p. 6999–7008

Constitutional isomers of cyanocobalamin adducts based on a fluorescent rhenium tris-carbonyl diimine complex were prepared, characterized and tested against PC-3 cancer cells. The adducts differ only in the relative binding position of the organometallic species which is either bound at the cyano or the 5′-hydroxo group of vitamin B₁₂. When tested for their cytotoxic potency, the species...