Université de Fribourg

Prevalence of fosfomycin resistance among ESBL-producing Escherichia coli isolates in the community, Switzerland

Mueller, Linda ; Cimen, Cansu ; Poirel, Laurent  ; Descombes, Marie-Christine  ; Nordmann, Patrice 

In: European Journal of Clinical Microbiology & Infectious Diseases, 2019, vol. 38, no. 5, p. 945–949

Our aim was to evaluate the prevalence of fosfomycin-resistant strains among ESBL- producing Escherichia coli isolates recovered from community patients in Switzerland. A total of 1225 ESBL-producing E. coli isolates were collected between 2012 and 2013 from a private and community laboratory. Fosfomycin resistance was assessed by using the novel rapid fosfomycin/E. coli NP test and agar...

Université de Fribourg

Rapid detection of fosfomycin resistance in Escherichia coli

Nordmann, Patrice ; Poirel, Laurent ; Mueller, Linda

In: Journal of Clinical Microbiology, 2019, vol. 57, no. 1, p. e01531-18

The rapid fosfomycin/Escherichia coli NP test was developed to detect fosfomycin resistance in E. coli isolates. The test is based on glucose metabolization and the detection of bacterial growth in the presence of fosfomycin at 40 µg/ml. Bacterial growth is visually detectable by an orange-to-yellow color change of red phenol, a pH indicator. A total of 100 E. coli isolates, among which 22...

Université de Fribourg

Comparative genome analysis of Pseudomonas knackmussii B13, the first bacterium known to degrade chloroaromatic compounds

Miyazaki, Ryo ; Bertelli, Claire ; Benaglio, Paola ; Canton, Jonas ; Coi, Nicoló De ; Gharib, Walid H. ; Gjoksi, Bebeka ; Goesmann, Alexander ; Greub, Gilbert ; Harshman, Keith ; Linke, Burkhard ; Mikulic, Josip ; Mueller, Linda ; Nicolas, Damien ; Robinson-Rechavi, Marc ; Rivolta, Carlo ; Roggo, Clémence ; Roy, Shantanu ; Sentchilo, Vladimir ; Siebenthal, Alexandra Von ; Falquet, Laurent ; Meer, Jan Roelof van der

In: Environmental Microbiology, 2014, p. -

Pseudomonas knackmussii B13 was the first strain to be isolated in 1974 that could degrade chlorinated aromatic hydrocarbons. This discovery was the prologue for subsequent characterization of numerous bacterial metabolic pathways, for genetic and biochemical studies, and which spurred ideas for pollutant bioremediation. In this study, we determined the complete genome sequence of B13 using...