Université de Neuchâtel

New approaches for the synthesis of advanced precursors of Rhazinilam analogues

Kholod Zaitseva, Inga ; Neier, Reinhard (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2014.

The purpose of this thesis was to explore different approaches for the synthesis of advanced precursors of rhazinilam analogues. The intramolecular Michael Addition was envisaged in order to obtain the pyrrole or pyrrolinone based analogues. The aim of the first project was to develop a flexible, efficient synthesis towards model systems. N-acylation and N-alkylation of the corresponding...