Université de Neuchâtel

Enhancement of Cytotoxicity by Combining Pyrenyl-Dendrimers and Arene Ruthenium Metallacages

Pitto-Barry, Anaïs ; Zava, Olivier ; Dyson, Paul J ; Deschenaux, Robert ; Therrien, Bruno

In: Inorganic Chemistry, 2012, vol. 51, no. 13, p. 7119-7124

Three generations of pyrenyl bis-MPA dendrimers with two different end-groups, acetonide (pyrGn) or alcohol (pyrGn-OH) (n = 1–3), were synthesized, and the pyrenyl group of the dendritic molecules was encapsulated in the arene ruthenium metallacages, [Ru6(p-cymene) 6 (OO∩OO)3(tpt)2]6+ (OO∩OO =...