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Université de Fribourg

Comparison of a novel biodegradable polymer sirolimus-eluting stent with a durable polymer everolimus-eluting stent: 5-year outcomes of the randomized bioflow-ii trial

Lefèvre, Thierry ; Haude, Michael ; Neumann, Franz-Josef ; Stang, Karl ; Skurk, Carsten ; Slagboom, Ton ; Sabaté, Manel ; Goicolea, Javier ; Barragan, Paul ; Cook, Stéphane ; Macia, Jean-Christophe ; Windecker, Stephan

In: JACC: Cardiovascular Interventions, 2018, vol. 11, no. 10, p. 995–1002

ObjectivesThe authors aimed to compare long-term data of an ultrathin cobalt- chromium stent with passive silicon carbide coating and an active biodegradable polymer that releases sirolimus (O-SES) (Orsiro, BIOTRONIK, Bülach, Switzerland) with the durable polymer-based Xience Prime everolimus-eluting stent (X-EES) (Abbott Vascular, Santa Clara, California).BackgroundBiodegradable polymer...

Université de Fribourg

Myocardial infarction stabilization by cell-based expression of controlled Vascular Endothelial Growth Factor levels

Melly, Ludovic ; Cerino, Giulia ; Frobert, Aurélien ; Cook, Stéphane ; Giraud, Marie-Noëlle ; Carrel, Thierry ; Tevaearai Stahel, Hendrik T. ; Eckstein, Friedrich ; Rondelet, Benoît ; Marsano, Anna ; Banfi, Andrea

In: Journal of Cellular and Molecular Medicine, 2018, p. -

Vascular Endothelial Growth Factor (VEGF) can induce normal or aberrant angiogenesis depending on the amount secreted in the microenvironment around each cell. Towards a possible clinical translation, we developed a Fluorescence Activated Cell Sorting (FACS)‐based technique to rapidly purify transduced progenitors that homogeneously express a desired specific VEGF level from heterogeneous...

Université de Fribourg

Transcutaneous aortic valve implantation using the carotid artery access: Feasibility and clinical outcomes

Kallinikou, Zacharenia ; Berger, Alexandre ; Ruchat, Patrick ; Khatchatourov, Gregory ; Fleisch, Isabelle ; Korkodelovic, Branislav ; Henchoz, Emmanuel ; Marti, René-Andréas ; Cook, Stéphane ; Togni, Mario ; Goy, Jean-Jacques

In: Archives of Cardiovascular Diseases, 2017, vol. 110, no. 6, p. 389–394

Background: Transcarotid access is an alternative route for transcutaneous aortic valve implantation (TAVI) in patients with impossible transfemoral access.Aims: We evaluated the safety, effectiveness and early and late clinical outcomes of CoreValve® implantation via the common carotid artery.Methods: Eighteen patients (10 men, 8 women; mean age 84 ± 5 years) at high surgical risk (mean...

Consortium of Swiss Academic Libraries

Optical coherence tomography findings in renal denervation

Cook, Stéphane ; Goy, Jean-Jacques ; Togni, Mario

In: European Heart Journal, 2012, vol. 33, no. 23, p. 2992-2992

Université de Fribourg

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?

Jain, Manish ; Zellweger, Matthieu ; Wagnières, Georges ; Bergh, Hubert van den ; Cook, Stéphane ; Giraud, Marie-Noëlle

In: Cardiovascular Therapeutics, 2017, vol. 35, no. 2, p. -

Acute coronary syndrome is a life-threatening condition of utmost clinical importance, which, despite recent progress in the field, is still associated with high morbidity and mortality. Acute coronary syndrome results from a rupture or erosion of vulnerable atherosclerotic plaque with secondary platelet activation and thrombus formation, which leads to partial or complete luminal obstruction...

Université de Fribourg

Late thrombotic events after bioresorbable scaffold implantation: a systematic review and meta-analysis of randomized clinical trials

Collet, Carlos ; Asano, Taku ; Miyazaki, Yosuke ; Tenekecioglu, Erhan ; Katagiri, Yuki ; Sotomi, Yohei ; Cavalcante, Rafael ; Winter, Robbert J. de ; Kimura, Takeshi ; Gao, Runlin ; Puricel, Serban ; Cook, Stéphane ; Capodanno, Davide ; Onuma, Yoshinobu ; Serruys, PatrickW.

In: European Heart Journal, 2017, p. -

To compare the long-term safety and efficacy of bioresorbable vascular scaffold (BVS) with everolimus-eluting stent (EES) after percutaneous coronary interventions.Methods and Results: A systematic review and meta-analysis of randomized clinical trials comparing clinical outcomes of patients treated with BVS and EES with at least 24 months follow-up was performed. Adjusted random-effect model...

Université de Fribourg

Heart rate never lies: interventional cardiologist and Braude’s quote revised

Cook, Stéphane ; Stauffer, Jean-Christophe ; Goy, Jean-Jacques ; Graf, Denis ; Puricel, Serban ; Frobert, Aurélien ; Muller, Olivier ; Togni, Mario ; Arroyo, Diego

In: Open Heart, 2016, vol. 3, no. 1, p. e000373

Background Interventional cardiologists may be immune to stress, allowing them to perform complex percutaneous interventions under pressure.Objectives To assess heart rate (HR) variations as a surrogate marker of stress of interventional cardiologists during percutaneous cardiac procedures and in every-day life.Design This is a single-centre...