Université de Neuchâtel

Sharing perception when using hands-on exhibits in science centres: the case of vocal depiction

Brandenberger, Christina ; Hottiger, Christoph

In: Revue Tranel, 2018, vol. 68, p. 59-68

There are various situations in our daily lives in which we share sensory perceptions in interaction, but research on how exactly we do this is relatively scarce and has often focused primarily on the visual and auditory channels. In this paper, we suggest an approach based on the methods of multimodal conversation analysis which also considers other perceptual fields, especially touch. By means...

Université de Fribourg

Quantification of gold nanoparticle cell uptake under controlled biological conditions and adequate resolution

Rothen-Rutishauser, Barbara ; Kuhn, Dagmar A ; Ali, Zulqurnain ; Gasser, Michael ; Amin, Faheem ; Parak, Wolfgang J ; Vanhecke, Dimitri ; Fink, Alke ; Gehr, Peter ; Brandenberger, Christina

In: Nanomedicine, 2014, vol. 9, no. 5, p. 607–621

Aim: We examined cellular uptake mechanisms of fluorescently labeled polymer-coated gold nanoparticles (NPs) under different biological conditions by two quantitative, microscopic approaches. Materials & methods: Uptake mechanisms were evaluated using endocytotic inhibitors that were tested for specificity and cytotoxicity. Cellular uptake of gold NPs was analyzed either by laser scanning...

Université de Fribourg

Can the Ames test provide an insight into nano-object mutagenicity? Investigating the interaction between nano-objects and bacteria

Clift, Martin J. D. ; Raemy, David O. ; Endes, Carola ; Ali, Zulqurnain ; Lehmann, Andrea D. ; Brandenberger, Christina ; Petri-Fink, Alke ; Wick, Peter ; Parak, Wolfgang J. ; Gehr, Peter ; Schins, Roel P. F. ; Rothen-Rutishauser, Barbara

In: Nanotoxicology, 2013, vol. 7, no. 8, p. 1373–1385

The aim of this study was to assess the interaction of a series of well characterised nano-objects with the Gram negative bacterium Salmonella typhimurium, and how such an interaction may relate to the potential mutagenicity of nano-objects. Transmission electron microscopy showed that nano-objects (Au-PMA-ATTO NPs, CeO₂ NPs, SWCNTs and MWCNTs), as well as CAFs entered S....