Université de Neuchâtel

The Acidic A-Domain of Arabidopsis Toc159 Occurs as a Hyperphosphorylated Protein

Agne, Birgit ; Andrès, Charles ; Montandon, Cyril ; Christ, Bastien ; Ertan, Anouk ; Jung, Friederike ; Infanger, Sibylle ; Bischof, Sylvain ; Baginsky, Sacha ; Kessler, Felix

In: Plant Physiology, 2010, vol. 53, no. 3, p. 1016-1030

The translocon at the outer membrane of the chloroplast assists the import of a large class of preproteins with amino-terminal transit sequences. The preprotein receptors Toc159 and Toc33 in Arabidopsis (Arabidopsis thaliana) are specific for the accumulation of abundant photosynthetic proteins. The receptors are homologous GTPases known to be regulated by phosphorylation within their...

Université de Neuchâtel

The TOC complex: Preprotein gateway to the chloroplast

Andrès, Charles ; Agne, Birgit ; Kessler, Felix

In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010, vol. 1803, no. 6, p. 715-723

Photosynthetic eukaryotes strongly depend on chloroplast metabolic pathways. Most if not all involve nuclear encoded proteins. These are synthesized as cytosolic preproteins with N-terminal, cleavable targeting sequences (transit peptide). Preproteins are imported by a major pathway composed of two proteins complexes: TOC and TIC (Translocon of the Outer and Inner membranes of the...