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Université de Fribourg

Coronary evaginations and peri-scaffold aneurysms following implantation of bioresorbable scaffolds: incidence, outcome, and optical coherence tomography analysis of possible mechanisms

Gori, Tommaso ; Jansen, Thomas ; Weissner, Melissa ; Foin, Nicolas ; Wenzel, Philip ; Schulz, Eberhard ; Cook, Stéphane ; Münzel, Thomas

In: European Heart Journal, 2016, vol. 37, no. 26, p. 2040–2049

Background Peri-stent coronary evaginations may disturb flow and have been proposed as possible risk factor for late stent thrombosis. We describe incidence, predictors, and possible mechanisms of coronary evaginations 12 months after implantation of bioresorbable vascular scaffolds (BVS).Methods and results One hundred and two BVS implanted in 90 patients...

Université de Fribourg

Driven colloidal fluids: construction of dynamical density functional theories from exactly solvable limits

Scacchi, Alberto ; Krüger, Matthias ; Brader, Joseph M

In: Journal of Physics: Condensed Matter, 2016, vol. 28, no. 24, p. 244023

The classical dynamical density functional theory (DDFT) provides an approximate extension of equilibrium DFT to treat nonequilibrium systems subject to Brownian dynamics. However, the method fails when applied to driven systems, such as sheared colloidal dispersions. The breakdown of DDFT can be traced back to an inadequate treatment of the flow-induced distortion of the pair correlation...

Université de Fribourg

Controlling colloidal sedimentation using time-dependent shear

Krüger, Matthias ; Brader, Joseph M.

In: Europhysics Letters, 2011, vol. 96, no. 6, p. 68006

Employing a recently developed dynamical density functional theory we consider the time-dependent response of a colloidal sediment above a wall to an externally applied shear flow, demonstrating the time-dependent changes of the density distribution and its center of mass after switching steady shear either on or off and under oscillatory shear. Following the onset of steady shear we identify two...

Université de Fribourg

Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis

Buschmann, Ivo ; Pries, Axel ; Styp-Rekowska, Beata ; Hillmeister, Philipp ; Loufrani, Laurent ; Henrion, Daniel ; Shi, Yu ; Duelsner, Andre ; Hoefer, Imo ; Gatzke, Nora ; Wang, Haitao ; Lehmann, Kerstin ; Ulm, Lena ; Ritter, Zully ; Hauff, Peter ; Hlushchuk, Ruslan ; Djonov, Valentin ; Veen, Toon van ; Le Noble, Ferdinand

In: Development, 2010, vol. 137, p. 2187-2196

In the developing chicken embryo yolk sac vasculature, the expression of arterial identity genes requires arterial hemodynamic conditions. We hypothesize that arterial flow must provide a unique signal that is relevant for supporting arterial identity gene expression and is absent in veins. We analyzed factors related to flow, pressure and oxygenation in the chicken embryo vitelline...