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Université de Fribourg

TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics

Zhu, Jinsheng ; Bailly, Aurelien ; Zwiewka, Marta ; Sovero, Valpuri ; Donato, Martin Di ; Ge, Pei ; Oehri, Jacqueline ; Aryal, Bibek ; Hao, Pengchao ; Linnert, Miriam ; Burgardt, Noelia Inés ; Lücke, Christian ; Weiwad, Matthias ; Michel, Max ; Weiergräber, Oliver H. ; Pollmann, Stephan ; Azzarello, Elisa ; Mancuso, Stefano ; Ferro, Noel ; Fukao, Yoichiro ; Hoffmann, Céline ; Wedlich-Söldner, Roland ; Friml, Jiří ; Thomas, Clément ; Geisler, Markus

In: The Plant Cell, 2016, vol. 28, no. 4, p. 930–948

Plant growth and architecture is regulated by the polar distribution of the hormone auxin. Polarity and flexibility of this process is provided by constant cycling of auxin transporter vesicles along actin filaments, coordinated by a positive auxin-actin feedback loop. Both polar auxin transport and vesicle cycling are inhibited by synthetic auxin transport inhibitors, such as...

Université de Fribourg

Multiple amplitude modes in strongly coupled phonon-mediated superconductors

Murakami, Yuta ; Werner, Philipp ; Tsuji, Naoto ; Aoki, Hideo

In: Physical Review B, 2016, vol. 93, no. 9, p. 94509

We study collective amplitude modes of the superconducting order parameter in strongly coupled electron-phonon systems described by the Holstein model using the nonequilibrium dynamical mean-field theory with the self-consistent Migdal approximation as an impurity solver. The frequency of the Higgs amplitude mode is found to coincide with the superconducting gap even in the strongly coupled...

Université de Fribourg

Keeping it all together : auxin–actin crosstalk in plant development

Zhu, Jinsheng ; Geisler, Markus

In: Journal of Experimental Botany, 2015, vol. 66, no. 16, p. 4983-4998

Polar auxin transport and the action of the actin cytoskeleton are tightly interconnected, which is documented by the finding that auxin transporters reach their final destination by active movement of secretory vesicles along F-actin tracks. Moreover, auxin transporter polarity and flexibility is thought to depend on transporter cycling that requires endocytosis and exocytosis of vesicles. In...

Université de Fribourg

The auxin transporter, OsAUX1, is involved in primary root and root hair elongation and in Cd stress responses in rice (Oryza sativa L.)

Yu, ChenLiang ; Sun, ChenDong ; Shen, Chenjia ; Wang, Suikang ; Liu, Fang ; Liu, Yan ; Chen, YunLong ; Li, Chuanyou ; Qian, Qian ; Aryal, Bibek ; Geisler, Markus ; Jiang, De An ; Qi, YanHua

In: The Plant Journal, 2015, vol. 83, no. 5, p. 818–830

Auxin and cadmium (Cd) stress play critical roles during root development. There are only a few reports on the mechanisms by which Cd stress influences auxin homeostasis and affects primary root (PR) and lateral root (LR) development, and almost nothing is known about how auxin and Cd interfere with root hair (RH) development. Here, we characterize rice osaux1 mutants that have a longer PR and...

Université de Fribourg

Superconductivity in the two-band Hubbard model

Koga, Akihisa ; Werner, Philipp

In: Physical Review B, 2015, vol. 91, no. 8, p. 085108

We study the two-band Hubbard model in infinite dimensions by solving the dynamical mean-field equations with a strong coupling continuous-time quantum Monte Carlo method and show that an s-wave superconducting state can be stabilized in the repulsively interacting case. We discuss how this superconducting state competes with the metallic and paired Mott states. The effects of the Hund coupling...

Université de Fribourg

Interaction quench in the Holstein model: Thermalization crossover from electron- to phonon-dominated relaxation

Murakami, Yuta ; Werner, Philipp ; Tsuji, Naoto ; Aoki, Hideo

In: Physical Review B, 2015, vol. 91, no. 4, p. 045128

We study the relaxation of the Holstein model after a sudden switch-on of the interaction by means of the nonequilibrium dynamical mean field theory, with the self-consistent Migdal approximation as an impurity solver. We show that there exists a qualitative change in the thermalization dynamics as the interaction is varied in the weak-coupling regime. On the weaker interaction side of this...

Université de Fribourg

The auxin response factor, OsARF19, controls rice leaf angles through positively regulating OsGH3-5 and OsBRI1

Zhang, Saina ; Wang, Suikang ; Xu, Yanxia ; Yu, Chenliang ; Shen, Chenjia ; Qian, Qian ; Geisler, Markus ; Jiang, De An ; Qi, Yanhua

In: Plant, Cell & Environment, 2014, p. –

Auxin and brassinosteroid (BR) are important phytohormones for controlling lamina inclination implicated in plant architecture and grain yield. But the molecular mechanism of auxin and BR crosstalk for regulating lamina inclination remains unknown. Auxin response factors (ARFs) control various aspects of plant growth and development. We here report that OsARF19-overexpression rice lines show an...

Université de Fribourg

Arabidopsis TWISTED DWARF1 functionally interacts with auxin exporter ABCB1 on the root plasma membrane

Wang, Bangjun ; Bailly, Aurélien ; Zwiewka, Marta ; Henrichs, Sina ; Azzarello, Elisa ; Mancuso, Stefano ; Maeshima, Masayoshi ; Friml, Jiří ; Schulz, Alexander ; Geisler, Markus

In: The Plant Cell, 2013, vol. 25, no. 1, p. 202-214

Plant architecture is influenced by the polar, cell-to-cell transport of auxin that is primarily provided and regulated by plasma membrane efflux catalysts of the PIN-FORMED and B family of ABC transporter (ABCB) classes. The latter were shown to require the functionality of the FK506 binding protein42 TWISTED DWARF1 (TWD1), although underlying mechanisms are unclear. By genetic manipulation of...

Université de Fribourg

Regulation of ABCB1/PGP1-catalysed auxin transport by linker phosphorylation

Henrichs, Sina ; Wang, Bangjun ; Fukao, Yoichiro ; Zhu, Jinsheng ; Charrier, Laurence ; Bailly, Aurélien ; Oehring, Sophie C ; Linnert, Miriam ; Weiwad, Matthias ; Endler, Anne ; Nanni, Paolo ; Pollmann, Stephan ; Mancuso, Stefano ; Schulz, Alexander ; Geisler, Markus

In: The EMBO Journal, 2012, p. -

Polar transport of the plant hormone auxin is controlled by PIN- and ABCB/PGP-efflux catalysts. PIN polarity is regulated by the AGC protein kinase, PINOID (PID), while ABCB activity was shown to be dependent on interaction with the FKBP42, TWISTED DWARF1 (TWD1). Using co-immunoprecipitation (co-IP) and shotgun LC–MS/MS analysis, we identified PID as a valid partner in the interaction with...

Université de Fribourg

Flavonols accumulate asymmetrically and affect auxin transport in Arabidopsis thaliana

Kuhn, Benjamin M. ; Geisler, Markus ; Bigler, Laurent ; Ringli, Christoph

In: Plant Physiology, 2011, p. -

Flavonoids represent a class of secondary metabolites with diverse functions in plants including UV protection, pathogen defence, and interspecies communication. They are also known as modulators of signalling processes in plant and animal systems and therefore are considered to have beneficial effects as nutraceuticals. The rol1-2 (repressor of lrx1) mutation of Arabidopsis...