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Graft preservation solutions in cardiovascular surgery

Winkler, Bernhard ; Reineke, David ; Heinisch, Paul Philip ; Schönhoff, Florian ; Huber, Christoph ; Kadner, Alexander ; Englberger, Lars ; Carrel, Thierry

In: Interactive CardioVascular and Thoracic Surgery, 2016, vol. 23, no. 2, p. 300-309

The Mre11-Nbs1 interface is essential for viability and tumor suppression

Kim, Jun Hyun ; Grosbart, Malgorzata ; Anand, Roopesh ; Wyman, Claire ; Cejka, Petr ; Petrini, John H.J.

In: Cell reports, 2017, vol. 18, no. 2, p. 496-507

The Mre11 complex (Mre11, Rad50, and Nbs1) is integral to both DNA repair and ataxia telangiectasia mutated (ATM)-dependent DNA damage signaling. All three Mre11 complex components are essential for viability at the cellular and organismal levels. To delineate essential and non-essential Mre11 complex functions that are mediated by Nbs1, we used TALEN-based genome editing to derive Nbs1...

Resolute zotarolimus‐eluting stent in ST‐elevation myocardial infarction (resolute‐STEMI): A prespecified prospective register from the DAPT‐STEMI trial

Postma, Warner ; Fabris, Enrico ; Ent, Martin Van der ; Hermanides, Rik ; Buszman, Pawel ; Birgelen, Clemens Von ; Cook, Stéphane ; Wedel, Hans ; Luca, Giuseppe De ; Delewi, Ronak ; Zijlstra, Felix ; Kedhi, Elvin

In: Catheterization and Cardiovascular Interventions, 2019, p. ccd.28376

To evaluate the safety and efficacy outcomes after primary percutaneous coronary intervention (pPCI) with second‐generation Resolute™ zotarolimus‐eluting stent (R‐ ZES) in patients enrolled in the DAPT‐STEMI Trial (NCT01459627).Background: R‐ ZES is one of the most used drug eluting stents worldwide. To date, the safety and efficacy data of this stent in setting of STEMI is...

Absorb bioresorbable scaffold versus xience metallic stent for prevention of restenosis following percutaneous coronary intervention in patients at high risk of restenosis: rationale and design of the COMPARE ABSORB trial

Chang, Chun Chin ; Onuma, Yoshinobu ; Achenbach, Stephan ; Barbato, Emanuele ; Chevalier, Bernard ; Cook, Stéphane ; Dudek, Dariusz ; Escaned, Javier ; Gori, Tommaso ; Kočka, Viktor ; Tarantini, Giuseppe ; E.J.West, Nick ; Morice, Marie-Claude ; G.P.Tijssen, Jan ; Geuns, Robert-Janvan ; C.Smits, Pieter

In: Cardiovascular Revascularization Medicine, 2019, vol. 20, no. 7, p. 577–582

Background: The advent of bioresorbable vascular scaffolds (BVS) was considered as a potential improvement in percutaneous coronary intervention (PCI) after the groundbreaking development of drug eluting stents (DES). However, the clinical performance, long-term safety and efficacy of BVS in complex coronary lesions remain uncertain. COMPARE ABSORB, a multicenter, single blind, prospective ...

Posterior auricular artery as an alternative donor vessel for extracranial-intracranial bypass surgery

Germans, Menno ; Regli, Luca

In: Acta Neurochirurgica, 2014, vol. 156, no. 11, p. 2095-2101

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome

Cassani, Barbara ; Poliani, Pietro Luigi ; Marrella, Veronica ; Schena, Francesca ; Sauer, Aisha V. ; Ravanini, Maria ; Strina, Dario ; Busse, Christian E. ; Regenass, Stephan ; Wardemann, Hedda ; Martini, Alberto ; Facchetti, Fabio ; Burg, Mirjam van der ; Rolink, Antonius G. ; Vezzoni, Paolo ; Grassi, Fabio ; Traggiai, Elisabetta ; Villa, Anna

In: Journal of experimental medicine, 2010, vol. 207, no. 7, p. 1525-1540

Hypomorphic RAG mutations, leading to limited V(D)J rearrangements, cause Omenn syndrome (OS), a peculiar severe combined immunodeficiency associated with autoimmune-like manifestations. Whether B cells play a role in OS pathogenesis is so far unexplored. Here we report the detection of plasma cells in lymphoid organs of OS patients, in which circulating B cells are undetectable. Hypomorphic...

Responders and non-responders in a study on medical end-of-life decisions in Denmark, the Netherlands, Sweden and Switzerland

Fischer, Susanne ; Miccinesi, Guido ; Hornung, Rainer ; Bosshard, Georg ; Deliens, Luc ; Heide, Agnes ; Nilstun, Tore ; Norup, Michael ; Onwuteaka-Philipsen, Bregje

In: Sozial- und Präventivmedizin, 2006, vol. 51, no. 1, p. 24-33

Right coronary artery chronic total occlusion in presence of anomalous origin of left coronary artery

D'Angeli, Ilaria ; Pedrazzini, Giovanni ; Faletra, Francesco

In: The International Journal of Cardiovascular Imaging, 2011, vol. 27, no. 1, p. 1-3

Percutaneous coronary interventions in Europe : Prevalence, numerical estimates, and projections based on data up to 2004

Cook, Stéphane ; Walker, Alexander ; Hügli, Olivier ; Togni, Mario ; Meier, Bernhard

In: Clinical Research in Cardiology, 2007, vol. 96, no. 6, p. 375-382

Transpulmonary lactate gradient after hypothermic cardiopulmonary bypass

Bendjelid, Karim ; Treggiari, Miriam ; Romand, Jacques-Andre

In: Intensive Care Medicine, 2004, vol. 30, no. 5, p. 817-821