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Université de Fribourg

Occurrence of NDM-1-producing Morganella morganii and Proteus mirabilis in a single patient in Portugal: probable in vivo transfer by conjugation

Aires-de-Sousa, Marta ; Ortiz de la Rosa, José Manuel ; Goncalves, Maria Luísa ; Costa, Augusto ; Nordmann, Patrice ; Poirel, Laurent

In: Journal of Antimicrobial Chemotherapy, 2020, vol. 75, no. 4, p. 903–906

To decipher the genetics of acquisition of carbapenemase-encoding genes identified in two carbapenem-resistant Enterobacteriaceae recovered from a single patient in Portugal.Methods: Carbapenemase genes were searched by PCR assays and mating-out assays were performed to further characterize the plasmid support of the carbapenemase genes. Genetic characterization of the plasmid supports was...

Université de Fribourg

M&A by Chinese POEs in developed countries : acquiring and bundling strategic assets

Wu, Juan ; Morschett, Dirk

(Working Papers SES ; 512)

Building on the resource-based view and based on 33 interviews with top executives of 11 Chinese private owned enterprises (POEs) and 15 Western target companies, this study is an in-depth multi-case analysis of Chinese crossborder merger and acquisitions. While literature has argued that acquisitions by Chinese companies in developed countries are motivated by asset-seeking, this study takes...

Université de Neuchâtel

Towards compact ultralow phase noise lasers and microwave signals based on new approaches

Brochard, Pierre ; Südmeyer, Thomas (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

Today, the lowest phase noise microwave signals are generated optically by frequency division of an ultra-stable optical reference using a femtosecond frequency comb. In the commonly used approach, the ultra-stable optical reference is obtained by frequency-stabilizing a laser to a high-finesse ultra-low expansion optical cavity, and the frequency division is performed by optically locking a...

Université de Fribourg

Telechelics based on catalytic alternating ring-opening metathesis polymerization

Pal, Subhajit ; Alizadeh, Mahshid ; Kilbinger, Andreas F. M.

In: ACS Macro Letters, 2019, vol. 8, no. 10, p. 1396–1401

We describe a protocol to synthesize alternating telechelic ROMP copolymers of 7- oxa-norbornene derivatives and cycloalkenes under catalytic conditions. These copolymers were synthesized using Grubbs’ second-generation catalyst. The sterically less hindered backbone double bonds of the resulting alternating copolymers facilitate the chain transfer (secondary metathesis) reactions. In the ...

Université de Fribourg

Catalytic living ring opening metathesis polymerisation: the importance of ring strain in chain transfer agents

Liu, Peng ; Yasir, Mohammad ; Kilbinger, Andreas F. M.

In: Angewandte Chemie International Edition, 2019, vol. 58, no. 43, p. 15278–15282

A recently developed catalytic living ring opening metathesis polymerisation (ROMP) was investigated using a series of reversible chain transfer agents (CTA) carrying either cyclopentene or cyclohexene rings, differing only in ring strain. All cyclopentene derivatives examined showed significantly faster reaction rates than the corresponding cyclohexene derivatives. This resulted in lower...

Université de Fribourg

Plasmon-assisted Förster resonance energy transfer at the single-molecule level in the moderate quenching regime

Bohlen, J. ; Cuartero-González, Á. ; Pibiri, E. ; Ruhlandt, D. ; Fernández-Domínguez, A. I. ; Tinnefeld, P. ; Acuna, Guillermo P.

In: Nanoscale, 2019, vol. 11, no. 16, p. 7674–7681

Metallic nanoparticles were shown to affect Förster energy transfer between fluorophore pairs. However, to date, the net plasmonic effect on FRET is still under dispute, with experiments showing efficiency enhancement and reduction. This controversy is due to the challenges involved in the precise positioning of FRET pairs in the near field of a metallic nanostructure, as well as in the...

Université de Fribourg

Changer le travail ou changer la société ? : Les hackers entre conformation à l'ordre social et volonté d'innover

Zufferey, Eric ; Surdez, Muriel (Dir.)

Thèse de doctorat : Université de Fribourg, 2018.

Changing workplace or society? Hackers between compliance with the social order and the will to innovate. This thesis looks at hacking as source of social change, or even subversion of the social order. Hacking involves self-directed learning and remove social barriers between hobbyists, professionals and activists. Therefore, it raises the hope to renew the access to knowledge and the role of...