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Exercise performed immediately after fructose ingestion enhances fructose oxidation and suppresses fructose storage

Egli, Léonie ; Lecoultre, Virgile ; Cros, Jérémy ; Rosset, Robin ; Marques, Anne-Sophie ; Schneiter, Philippe ; Hodson, Leanne ; Gabert, Laure ; Laville, Martine ; Tappy, Luc

In: The American Journal of Clinical Nutrition, 2016, vol. 103, no. 2, p. 348-355

The extended, dynamic mitochondrial reticulum in skeletal muscle and the creatine kinase (CK)/phosphocreatine (PCr) shuttle are working hand in hand for optimal energy provision

Wallimann, Theo

In: Journal of Muscle Research and Cell Motility, 2015, vol. 36, no. 4-5, p. 297-300

FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase

Imeri, Faik ; Blanchard, Olivier ; Jenni, Aurelio ; Schwalm, Stephanie ; Wünsche, Christin ; Zivkovic, Aleksandra ; Stark, Holger ; Pfeilschifter, Josef ; Huwiler, Andrea

In: Naunyn-Schmiedeberg's Archives of Pharmacology, 2015, vol. 388, no. 12, p. 1283-1292

Cellular, biochemical and molecular changes in muscles from patients with X-linked myotubular myopathy due to MTM1 mutations

Bachmann, Christoph ; Jungbluth, Heinz ; Muntoni, Francesco ; Manzur, Adnan Y. ; Zorzato, Francesco ; Treves, Susan

In: Human Molecular Genetics, 2017, vol. 26, no. 2, p. 320-332

Postexercise repletion of muscle energy stores with fructose or glucose in mixed meals

Rosset, Robin ; Lecoultre, Virgile ; Egli, Léonie ; Cros, Jérémy ; Dokumaci, Ayse Sila ; Zwygart, Karin ; Boesch, Chris ; Kreis, Roland ; Schneiter, Philippe ; Tappy, Luc

In: The American Journal of Clinical Nutrition, 2017, vol. 105, no. 3, p. 609-617

Role of akt activation in PARP inhibitor resistance in cancer

Gallyas, Ferenc ; Sumegi, Balazs ; Szabo, Csaba

In: Cancers, 2020, vol. 12, no. 3, p. 532

Poly(ADP-ribose) polymerase (PARP) inhibitors have recently been introduced in the therapy of several types of cancers not responding to conventional treatments. However, de novo and acquired PARP inhibitor resistance is a significant limiting factor in the clinical therapy, and the underlying mechanisms are not fully understood. Activity of the cytoprotective phosphatidylinositol-3 kinase...

MAGI1 mediates eNOS activation and NO production in endothelial cells in response to fluid shear stress

Ghimire, Kedar ; Zaric, Jelena ; Alday-Parejo, Begoña ; Seebach, Jochen ; Bousquenaud, Mélanie ; Stalin, Jimmy ; Bieler, Grégory ; Schnittler, Hans-Joachim ; Rüegg, Curzio

In: Cells, 2019, vol. 8, no. 5, p. 388

Fluid shear stress stimulates endothelial nitric oxide synthase (eNOS) activation and nitric oxide (NO) production through multiple kinases, including protein kinase A (PKA), AMP-activated protein kinase (AMPK), AKT and Ca2+/calmodulin-dependent protein kinase II (CaMKII). Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an adaptor protein that...

The effect of a single 2h bout of aerobic exercise on ectopic lipids in skeletal muscle, liver and the myocardium

Bucher, Julie ; Krüsi, Marion ; Zueger, Thomas ; Ith, Michael ; Stettler, Christoph ; Diem, Peter ; Boesch, Chris ; Kreis, Roland ; Christ, Emanuel

In: Diabetologia, 2014, vol. 57, no. 5, p. 1001-1005

Pathophysiological mechanisms of catecholamine and cocaine-mediated cardiotoxicity

Liaudet, Lucas ; Calderari, Belinda ; Pacher, Pal

In: Heart Failure Reviews, 2014, vol. 19, no. 6, p. 815-824

The dietary protein, IGF-I, skeletal health axis

Bonjour, Jean-Philippe

In: Hormone Molecular Biology and Clinical Investigation, 2016, vol. 28, no. 1, p. 39-53