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Université de Fribourg

Rapid genomic and phenotypic change in response to climate warming in a widespread plant invader

Sun, Yan ; Bossdorf, Oliver ; Grados, Ramon D. ; Liao, Zhi, Yong ; Müller‐Schärer, Heinz

In: Global Change Biology, 2020//n/a/-

Predicting plant distributions under climate change is constrained by our limited understanding of potential rapid adaptive evolution. In an experimental evolution study with the invasive common ragweed (Ambrosia artemisiifolia L.) we subjected replicated populations of the same initial genetic composition to simulated climate warming. Pooled DNA sequencing of parental and offspring...

Université de Fribourg

Drosophila germ-line modulation of insulin signaling and lifespan

Flatt, Thomas ; Min, Kyung-Jin ; D'Alterio, Cecilia ; Villa-Cuesta, Eugenia ; Cumbers, John ; Lehmann, Ruth ; Jones, D. Leanne ; Tatar, Marc

In: Proceedings of the National Academy of Sciences of the United States of America, 2008, vol. 105, no. 17, p. 6368–6373

Ablation of germ-line precursor cells in Caenorhabditis elegans extends lifespan by activating DAF-16, a forkhead transcription factor (FOXO) repressed by insulin/insulin-like growth factor (IGF) signaling (IIS). Signals from the gonad might thus regulate whole-organism aging by modulating IIS. To date, the details of this systemic regulation of aging by the reproductive system are not...

Consortium of Swiss Academic Libraries

RNA turnover and chromatin-dependent gene silencing

Bühler, Marc

In: Chromosoma, 2009, vol. 118, no. 2, p. 141-151