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Université de Fribourg

Mitochondrial sphingosine-1-phosphate lyase is essential for phosphatidylethanolamine synthesis and survival of Trypanosoma brucei

Dawoody Nejad, Ladan ; Stumpe, Michael ; Rauch, Monika ; Hemphill, Andrew ; Schneiter, Roger ; Bütikofer, Peter ; Serricchio, Mauro

In: Scientific Reports, 2020, vol. 10, no. 1, p. 8268

Sphingosine-1-phosphate is a signaling molecule involved in the control of cell migration, differentiation, survival and other physiological processes. This sphingolipid metabolite can be degraded by the action of sphingosine-1-phosphate lyase (SPL) to form hexadecenal and ethanolamine phosphate. The importance of SPL-mediated ethanolamine phosphate formation has been characterized in only...

Université de Fribourg

Comparing thyroid and insect hormone signaling

Flatt, Thomas ; Moroz, Leonid L. ; Tatar, Marc ; Heyland, Andreas

In: Integrative and Comparative Biology, 2006, vol. 46, no. 6, p. 777-794

Transitions between different states of development, physiology, and life history are typically mediated by hormones. In insects, metamorphosis and reproductive maturation are regulated by an interaction between the sesquiterpenoid juvenile hormone (JH) and the steroid 20-hydroxy-ecdysone (20E). In vertebrates and some marine invertebrates, the lipophilic thyroid hormones (THs) affect...

Consortium of Swiss Academic Libraries

Human African trypanosomiasis in endemic populations and travellers

Blum, J. ; Neumayr, A. ; Hatz, C.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2012, vol. 31, no. 6, p. 905-913

Consortium of Swiss Academic Libraries

Aldehyde dehydrogenase in tobacco pollen

op den Camp, Roel ; Kuhlemeier*, Cris

In: Plant Molecular Biology, 1997, vol. 35, no. 3, p. 355-365