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Università della Svizzera italiana

Psychological impact of COVID-19 outbreak on families of children with autism spectrum disorder and typically developing peers : an online survey

Levante, Annalisa ; Petrocchi, Serena ; Bianco, Federica ; Castelli, Ilaria ; Colombi, Costanza ; Keller, Roberto ; Narzisi, Antonio ; Masi, Gabriele ; Lecciso, Flavia

In: Brain sciences, 2021, vol. 11, no. 6, p. 16

When COVID-19 was declared as a pandemic, many countries imposed severe lockdowns that changed families’ routines and negatively impacted on parents’ and children’s mental health. Several studies on families with children with autism spectrum disorder (ASD) revealed that lockdown increased the difficulties faced by individuals with ASD, as well as parental distress. No studies have...

Università della Svizzera italiana

Head-to-head comparison of FNA cytology vs. calcitonin measurement in FNA washout fluids (FNA-CT) to diagnose medullary thyroid carcinoma : A systematic review and meta-analysis

Trimboli, Pierpaolo ; Giannelli, Jacopo ; Marques, Bernardo ; Piccardo, Arnoldo ; Crescenzi, Anna ; Deandrea, Maurilio

In: Endocrine, 2022, no. 75, p. 33–39

Purpose: The sensitivity of cytology after fine needle aspiration (FNA-cytology) in detecting medullary thyroid carcinoma (MTC) is low. To overcome this problem, measuring calcitonin (CT) in washout fluid of FNA (FNA-CT) has been largely diffused and showed good performance. However, no evidence-based study exists comparing systematically the sensitivity of FNA-cytology and FNA-CT. This study...

Università della Svizzera italiana

Maternal psychological distress and children’s internalizing/externalizing problems during the COVID-19 pandemic : the moderating role played by hypermentalization

Bianco, Federica ; Levante, Annalisa ; Petrocchi, Serena ; Lecciso, Flavia ; Castelli, Ilaria

In: International journal of environmental research and public health, 2021, vol. 18, no. 19, p. 17

In order to explore the psychological impact of the COVID‐19 outbreak on the caregiver–child relationship, we investigated the interplay among COVID‐19 exposure and children’s internalizing/externalizing problems during the Italian lockdown, hypothesizing a mediation effect played by maternal distress. Additionally, we included maternal reflective functioning (i.e., hypermentalization)...

Università della Svizzera italiana

Artificial intelligence in thyroid field : a comprehensive review

Bini, Fabiano ; Pica, Andrada ; Azzimonti, Laura ; Giusti, Alessandro ; Ruinelli, Lorenzo ; Marinozzi, Franco ; Trimboli, Pierpaolo

In: Cancers, 2021, vol. 13, no. 19, p. 18

Artificial intelligence (AI) uses mathematical algorithms to perform tasks that require human cognitive abilities. AI-based methodologies, e.g., machine learning and deep learning, as well as the recently developed research field of radiomics have noticeable potential to transform medical diagnostics. AI-based techniques applied to medical imaging allow to detect biological abnormalities, to...

Università della Svizzera italiana

Causal impacts of epidemics and pandemics on food supply chains : a systematic review

Cardoso, Brenda ; Cunha, Luiza ; Leiras, Adriana ; Gonçalves, Paulo ; Yoshizaki, Hugo ; de Brito Junior, Irineu ; Pedroso, Frederico

In: Sustainability, 2021, vol. 13, no. 17, p. 28

The epidemics and pandemics can severely affect food supply chains, including producers, retailers, wholesalers, and customers. To minimize their impacts, it is fundamental to implement effective policies that ensure continuity in the provision, affordability, and distribution of basic food items. This research identifies the main impacts of pandemics and epidemics on food supply chains and ...

Università della Svizzera italiana

Non-alcoholic fatty liver disease : metabolic, genetic, epigenetic and environmental risk factors

Juanola, Oriol ; Martínez-López, Sebastián ; Francés, Rubén ; Gómez-Hurtado, Isabel

In: International journal of environmental research and public health, 2021, vol. 18, no. 10, p. 24

Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver disease in the Western world, probably due to the growing prevalence of obesity, metabolic diseases, and exposure to some environmental agents. In certain patients, simple hepatic steatosis can progress to non-alcoholic steatohepatitis (NASH), which can sometimes lead to liver cirrhosis and its...

Università della Svizzera italiana

Willingness to vaccinate against Covid-19 : a qualitative study involving older adults from Southern Switzerland

Fadda, Marta ; Suggs, L. Suzanne ; Albanese, Emiliano

In: Vaccine: X, 2021, vol. 8, p. 7

Background: The Covid-19 pandemic is causing unprecedented disruption and suffering to people across the globe, with a disproportionate toll on the elderly. The development and equitable distribution of a vaccine seems to be the most promising and sustainable route ahead. The goal of this study was to explore older adults’ attitudes towards and beliefs regarding the Covid-19 vaccination in...

Università della Svizzera italiana

Reporting of acute inflammatory neuropathies with COVID-19 vaccines : subgroup disproportionality analyses in VigiBase

Noseda, Roberta ; Ripellino, Paolo ; Ghidossi, Sara ; Bertoli, Raffaela ; Ceschi, Alessandro

In: Vaccines, 2021, vol. 9, no. 9, p. 7

Since marketing authorization, cases of neuralgic amyotrophy (NA), facial paralysis/Bell’s palsy (FP/BP), and Guillain-Barré syndrome (GBS) were reported with COVID-19 vaccines of different technologies. This study aimed to assess whether NA, FP/BP, and GBS were more frequently reported in VigiBase with COVID-19 vaccines (of any technologies) than with other viral vaccines, over the full...

Università della Svizzera italiana

Prevalence of physiological uptake in the pancreas on somatostatin receptor-based PET/CT : a systematic review and a meta-analysis

Boughdad, Sarah ; Meyer, Marie ; Prior, John O. ; Fernandes, Victor ; Allenbach, Gilles ; Kamani, Christel ; Jreige, Mario ; Albano, Domenico ; Bertagna, Francesco ; Nicod-Lalonde, Marie ; Schaefer, Niklaus ; Treglia, Giorgio

In: Clinical and Translational Imaging, 2021, vol. 9, no. 4, p. 353–360

Background: Physiological focal radiopharmaceutical uptake in the head and uncinate process of the pancreas may be seen on somatostatin receptor-based PET/CT and might lead to false-positive results for neuroendocrine tumours (NETs). We aimed to perform a systematic review and a meta-analysis about the prevalence of this finding. Methods: We performed a comprehensive computer literature search...

Università della Svizzera italiana

Thyroid sequelae of COVID-19 : a systematic review of reviews

Trimboli, Pierpaolo ; Camponovo, Chiara ; Scappaticcio, Lorenzo ; Bellastella, Giuseppe ; Piccardo, Arnoldo ; Rotondi, Mario

In: Reviews in Endocrine and Metabolic Disorders, 2021, vol. 22, no. 2, p. 485-491

The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential to cause multi- organ effects including endocrine disorders. The impact of COVID-19 on the thyroid gland has been described but several aspects have to be clarified. The systematic review was conceived to achieve more solid information about: 1) which thyroid...