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Università della Svizzera italiana

Effect of lactose pseudopolymorphic transition on the aerosolization performance of drug/carrier mixtures

Della Bella, Andrea ; Müller, Michele ; Danani, Andrea ; Soldati, Luciano ; Bettini, Ruggero

In: Pharmaceutics, 2019, vol. 11, no. 11, p. 576

Physico-chemical properties of lactose are key factors in adhesive mixtures used as dry powder inhaler (DPI). Despite the abundant literature on this topic, the effect of the polymorphism and pseudo-polymorphism of lactose has been seldom investigated and discussed although often lactose used in DPI is subjected to unit operations, which may alter its solid-state properties. Here, we studied...

Università della Svizzera italiana

Bayesian dependence tests for continuous, binary and mixed continuous-binary variables

Benavoli, Alessio ; De Campos, Cassio P.

In: Entropy, 2016, vol. 18, no. 9, p. 326

Tests for dependence of continuous, discrete and mixed continuous-discrete variables are ubiquitous in science. The goal of this paper is to derive Bayesian alternatives to frequentist null hypothesis significance tests for dependence. In particular, we will present three Bayesian tests for dependence of binary, continuous and mixed variables. These tests are nonparametric and based on the...

Consortium of Swiss Academic Libraries

Poly-acrylic Acid Brushes and Adsorbed Proteins

Reinhardt, Matthias ; Kreuzer, Martin ; Geue, Thomas ; Dahint, Reiner ; Ballauff, Matthias ; Steitz, Roland

In: Zeitschrift für Physikalische Chemie, 2015, vol. 229, no. 7-8, p. 1119-1139