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Are admission procalcitonin levels universal mortality predictors across different medical emergency patient populations? Results from the multi-national, prospective, observational TRIAGE study

Sager, Ramon ; Wirz, Yannick ; Amin, Devendra ; Amin, Adina ; Hausfater, Pierre ; Huber, Andreas ; Haubitz, Sebastian ; Kutz, Alexander ; Mueller, Beat ; Schuetz, Philipp

In: Clinical Chemistry and Laboratory Medicine (CCLM), 2017, vol. 55, no. 12, p. 1873-1880

Kolmogorov-Smirnov like test for time-frequency Fourier spectrogram analysis in LISA Pathfinder

Ferraioli, Luigi ; Armano, Michele ; Audley, Heather ; Congedo, Giuseppe ; Diepholz, Ingo ; Gibert, Ferran ; Hewitson, Martin ; Hueller, Mauro ; Karnesis, Nikolaos ; Korsakova, Natalia ; Nofrarias, Miquel ; Plagnol, Eric ; Vitale, Stefano

In: Experimental Astronomy, 2015, vol. 39, no. 1, p. 1-10

Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible

Biosse Duplan, Martin ; Komla-Ebri, Davide ; Heuzé, Yann ; Estibals, Valentin ; Gaudas, Emilie ; Kaci, Nabil ; Benoist-Lasselin, Catherine ; Zerah, Michel ; Kramer, Ina ; Kneissel, Michaela ; Porta, Diana Grauss ; Di Rocco, Federico ; Legeai-Mallet, Laurence

In: Human Molecular Genetics, 2016, vol. 25, no. 14, p. 2997-3010

Randomized, placebo-controlled, double-blind clinical trial to evaluate the efficacy of polyhexanide for topical decolonization of MRSA carriers

Landelle, C. ; von Dach, E. ; Haustein, T. ; Agostinho, A. ; Renzi, G. ; Renzoni, A. ; Pittet, D. ; Schrenzel, J. ; François, P. ; Harbarth, S.

In: Journal of Antimicrobial Chemotherapy, 2016, vol. 71, no. 2, p. 531-538

Cross-border emergence of clonal lineages of ST38 Escherichia coli producing the OXA-48-like carbapenemase OXA-244 in Germany and Switzerland

Falgenhauer, Linda ; Nordmann, Patrice ; Imirzalioglu, Can ; Yao, Yancheng ; Falgenhauer, Jane ; M.Hauri, Anja ; Heinmüller, Petra ; Chakraborty, Trinad

In: International Journal of Antimicrobial Agents, 2020, vol. 56, no. 6, p. 106157

Background: Carbapenemase-producing Gram-negative bacteria cause infections that are difficult to treat and represent a rising threat to healthcare systems worldwide. This study analysed isolates of Escherichia coli (E. coli), a species associated with nosocomial-acquired and community-acquired infections, from hospitals in Germany and Switzerland exhibiting a slight decrease in...

Rapid ESBL NP test for rapid detection of expanded-spectrum β-lactamase producers in enterobacterales

Demord, Anthony ; Poirel, Laurent ; D'Emidio, Fernando ; Pomponio, Stefano ; Nordmann, Patrice

In: Microbial Drug Resistance, 2020, p. -

Objectives: To evaluate the biochemical Rapid ESBL NP® (Liofilchem, Italy) for the rapid detection of extended-spectrum β-lactamases (ESBLs) in Enterobacterales.Methods: A total of 100 clinical gram-negative strains (40 ESBL producers with or without cephalosporinase, 43 carbapenemase producers with or without additional ESBLs, 8 AmpC-type producers, 6 penicillinase producers, and 3 ...

High colonization rate and heterogeneity of ESBL- and carbapenemase-producing enterobacteriaceae isolated from gull feces in Lisbon, Portugal

Aires-de-Sousa, Marta ; Fournier, Claudine ; Lopes, Elizeth ; Lencastre, Hermínia de ; Nordmann, Patrice ; Poirel, Laurent

In: Microorganisms, 2020, vol. 8, no. 10, p. 1487

In order to evaluate whether seagulls living on the Lisbon coastline, Portugal, might be colonized and consequently represent potential spreaders of multidrug-resistant bacteria, a total of 88 gull fecal samples were screened for detection of extended- spectrum β-lactamase (ESBL)- or carbapenemase-producing Enterobacteriaceae for methicillin-resistant Staphylococcus aureus (MRSA) and for...

Epidemiology of extended-spectrum β-lactamase-producing Enterobacteriaceae among healthcare students, at the Portuguese Red Cross Health School of Lisbon, Portugal

Fournier, Claudine ; Aires de Sousa, Marta ; Fuster Escriva, Begoña ; Sales, Leila ; Nordmanna, Patrice ; Poirel, Laurent

In: Journal of Global Antimicrobial Resistance, 2020, vol. 22, p. 733–737

Objective: The aim of the present study was to prospectively evaluate the prevalence of intestinal carriage by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae among Portuguese students attending a Bachelors’ course in healthcare, and to determine the molecular features of ESBL-producing isolates.Methods: One-hundred and eleven faecal samples recovered from Portuguese...

Diabetes mellitus is a risk factor for prolonged SARS-CoV-2 viral shedding in lower respiratory tract samples of critically ill patients

Buetti, Niccolò ; Trimboli, Pierpaolo ; Mazzuchelli, Timothy ; Lo Priore, Elia ; Balmelli, Carlo ; Trkola, Alexandra ; Conti, Marco ; Martinetti, Gladys ; Elzi, Luigia ; Ceschi, Alessandro ; Consonni, Vera ; Ogna, Adam ; Forni-Ogna, Valentina ; Bernasconi, Enos

In: Endocrine, 2020, p. 7 p

The length of time a critically ill coronavirus disease 2019 (COVID-19) patient remains infectious and should therefore be isolated remains unknown. This prospective study was undertaken in critically ill patients to evaluate the reliability of single negative real-time polymerase chain reaction (RT-PCR) in lower tracheal aspirates (LTA) in predicting a second negative test and to analyze...

Optimal detection of extended-spectrum β-lactamase producers, carbapenemase producers, polymyxin-resistant Enterobacterales, and vancomycin-resistant enterococci from stools

Sadek, Mustafa ; Poirel, Laurent ; Nordmann, Patrice

In: Diagnostic Microbiology and Infectious Disease, 2020, vol. 96, no. 1, p. 114919

This study compared the impact of different approaches, namely, nonenrichment, nonselective enrichment, and selective (antibiotic-containing) enrichment steps, for detecting extended-spectrum β-lactamase producing Enterobacterales (ESBL-E), carbapenemase-producing Enterobacterales (CPE), polymyxin-resistant Enterobacterales (PMR-E), and vancomycin- resistant enterococci (VRE) from spiked...