Refine my results

Document type

Specific Collection

Language

Université de Fribourg

Slow-targeted release of a ruthenium anticancer agent from vitamin B 12 functionalized marine diatom microalgae

Delasoie, Joachim ; Rossier, Jérémie ; Haeni, Laetitia ; Rothen-Rutishauser, Barbara ; Zobi, Fabio

In: Dalton Transactions, 2018, vol. 47, no. 48, p. 17221–17232

Herein we report the synthesis of a new biomaterial designed for targeted delivery of poorly water-soluble inorganic anticancer drugs, with a focus on colorectal cancer. Diatomaceous earth microparticles derived from marine microalgae were coated with vitamin B12 (cyanocobalamin) as a tumor targeting agent and loaded with the well- known anticancer agents cisplatin, 5-fluorouracil (5-FU), and...

Consortium of Swiss Academic Libraries

Recent Trends in Biomimetic NADH Regeneration

Quinto, Tommaso ; Köhler, Valentin ; Ward, Thomas

In: Topics in Catalysis, 2014, vol. 57, no. 5, p. 321-331

Université de Fribourg

Catalytic living ring-opening metathesis polymerization with Grubbs’ second- and third-generation catalysts

Yasir, Mohammad ; Liu, Peng ; Tennie, Iris K. ; Kilbinger, Andreas F. M.

In: Nature Chemistry, 2019, vol. 11, no. 5, p. 488–494

In a conventional living ring-opening metathesis polymerization (ROMP), an equal number of ruthenium complexes to the number of polymer chains synthesized are required. This can lead to high loadings of ruthenium complexes when aiming for shorter polymers. Here, a reversible chain-transfer agent was used to produce living ROMP polymers from norbornene derivatives using catalytic amounts of...

Université de Fribourg

Heptacoordinate Co(II) catalyst for light-driven hydrogen production in fully aqueous medium

Lucarini, Fiorella ; Ruggi, Albert

In: CHIMIA International Journal for Chemistry, 2018, vol. 72, no. 4, p. 203–206

Photocatalytic hydrogen production is an appealing way to store solar energy as chemical fuel. The most studied molecular catalysts for H2 production are based on earth-abundant metals such as Ni, Co and Fe. Efforts have been recently focused on the design of Co complexes with distorted octahedral geometries induced by tetra- or pentapyridyl ligands. We synthesized a new Co(II) complex based...