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Università della Svizzera italiana

The N276 glycosylation site is required for HIV-1 neutralization by the CD4 binding site specific HJ16 monoclonal antibody

Balla-Jhagjhoorsingh, Sunita S. ; Corti, Davide ; Heyndrickx, Leo ; Willems, Elisabeth ; Vereecken, Katleen ; Davis, David ; Vanham, Guido

In: Plos one, 2013, vol. 8, no. 7, p. e68863

Immunogen design for HIV-1 vaccines could be based on epitope identification of naturally occurring neutralizing antibodies in infected patients. A tier 2 neutralizing monoclonal antibody (mAb), HJ16 recognizes a new epitope in the CD4 binding site (CD4bs) region that only partially overlaps with the b12 epitope. We aimed to identify the critical binding site by resistance induction in a...

Université de Fribourg

Corticotectal projections from the premotor or primary motor cortex after cortical lesion or parkinsonian symptoms in adult macaque monkeys: a pilot tracing study

Fregosi, Michela ; Contestabile, Alessandro ; Badoud, Simon ; Borgognon, Simon ; Cottet, Jérôme ; Brunet, Jean-François ; Bloch, Jocelyne ; Schwab, Martin E. ; Rouiller, Eric M.

In: Frontiers in Neuroanatomy, 2019, vol. 13, p. -

The corticotectal projections, together with the corticobulbar (corticoreticular) projections, work in parallel with the corticospinal tract (CST) to influence motoneurons in the spinal cord both directly and indirectly via the brainstem descending pathways. The tectospinal tract (TST) originates in the deep layers of the superior colliculus. In the present study, we analyzed the...

Consortium of Swiss Academic Libraries

Fc Glycan-Modulated Immunoglobulin G Effector Functions

Quast, Isaak ; Lünemann, Jan

In: Journal of Clinical Immunology, 2014, vol. 34, p. 51-55

Université de Fribourg

Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics

Capogrosso, Marco ; Wagner, Fabien B. ; Gandar, Jerome ; Moraud, Eduardo Martin ; Wenger, Nikolaus ; Milekovic, Tomislav ; Shkorbatova, Polina ; Pavlova, Natalia ; Musienko, Pavel ; Bezard, Erwan ; Bloch, Jocelyne ; Courtine, Grégoire

In: Nature Protocols, 2018, vol. 13, no. 9, p. 2031–2061

Epidural electrical stimulation (EES) of the spinal cord and real-time processing of gait kinematics are powerful methods for the study of locomotion and the improvement of motor control after injury or in neurological disorders. Here, we describe equipment and surgical procedures that can be used to acquire chronic electromyographic (EMG) recordings from leg muscles and to implant targeted...

Consortium of Swiss Academic Libraries

Comparison of five commercial serological tests for the detection of anti- Chlamydia trachomatis antibodies

Baud, D. ; Regan, L. ; Greub, G.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2010, vol. 29, no. 6, p. 669-675

Consortium of Swiss Academic Libraries

Anti-retinal autoantibodies in experimental ocular and systemic toxoplasmosis

Garweg, Justus ; de Kozak, Yvonne ; Goldenberg, Brigitte ; Boehnke, Matthias

In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2010, vol. 248, no. 4, p. 573-584