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Université de Fribourg

Computational network biology: Data, models, and applications

Liu, Chuang ; Ma, Yifang ; Zhao, Jing ; Nussinov, Ruth ; Zhang, Yi-Cheng ; Cheng, Feixiong ; Zhang, Zi-Ke

In: Physics Reports, 2020, vol. 846, p. 1–66

Biological entities are involved in intricate and complex interactions, in which uncovering the biological information from the network concepts are of great significance. Benefiting from the advances of network science and high-throughput biomedical technologies, studying the biological systems from network biology has attracted much attention in recent years, and networks have long been...

Université de Fribourg

Predicting financial extremes based on weighted visual graph of major stock indices

Chen, Dong-Rui ; Liu, Chuang ; Zhang, Yi-Cheng ; Zhang, Zi-Ke

In: Complexity, 2019, vol. 2019, p. 1–17

Understanding and predicting extreme turning points in the financial market, such as financial bubbles and crashes, has attracted much attention in recent years. Experimental observations of the superexponential increase of prices before crashes indicate the predictability of financial extremes. In this study, we aim to forecast extreme events in the stock market using 19-year time-series...

Université de Fribourg

The auxin influx carrier, OsAUX3, regulates rice root development and responses to aluminium stress

Wang, Mei ; Qiao, JiYue ; Yu, ChenLiang ; Chen, Hao ; Sun, ChenDong ; Huang, LinZhou ; Li, ChuanYou ; Geisler, Markus ; Qian, Qian ; Jiang, De An ; Qi, YanHua

In: Plant, Cell & Environment, 2019, vol. 42, no. 4, p. 1125–1138

In rice, there are five members of the auxin carrier AUXIN1/LIKE AUX1 family; however, the biological functions of the other four members besides OsAUX1 remain unknown. Here, by using CRISPR/Cas9, we constructed two independent OsAUX3 knock‐down lines, osaux3‐1 and osaux3‐2, in wild‐type rice, Hwayoung (WT/HY) and Dongjin (WT/DJ). osaux3‐1 and osaux3‐2 have shorter primary roots...