In: International Mathematics Research Notices, 2017, vol. 2017, no. 8, p. 2367-2401
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In: Annals of Probability, 2020, vol. 48, no. 4, p. 1644–1692
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In: Published version; http://dx.doi.org/10.1007/s11357-019-00095-x, 2019, p. -
Understanding molecular mechanisms involved in vascular aging is essential to develop novel interventional strategies for treatment and prevention of age-related vascular pathologies. Recent studies provide critical evidence that vascular aging is characterized by NAD+ depletion. Importantly, in aged mice, restoration of cellular NAD+ levels by treatment with the NAD+ booster nicotinamide...
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In: Scientific Reports, 2019, vol. 9, no. 1, p. 1–18
The chromobox homolog 2 (CBX2) was found to be important for human testis development, but its role in the human ovary remains elusive. We conducted a genome-wide analysis based on DNA adenine methyltransferase identification (DamID) and RNA sequencing strategies to investigate CBX2 in the human granulosa cells. Functional analysis revealed that CBX2 was upstream of genes contributing to ...
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In: Pharmacological Research, 2019, vol. 145, p. 104263
Poly(ADP-ribose) polymerase (PARP) is involved in the pathogenesis of cell dysfunction, inflammation and organ failure during septic shock. The goal of the current study was to investigate the efficacy and safety of the clinically approved PARP inhibitor olaparib in experimental models of oxidative stress in vitro and in sepsis in vivo. In mice subjected to cecal ligation and puncture (CLP)...
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In: Scientific Reports, 2018, vol. 8, no. 1, p. 10806
A little known, unculturable ascomycete, referred to as Phyllachora ambrosiae, can destroy the inflorescences of Ambrosia artemisiifolia, an invasive agricultural weed and producer of highly allergenic pollen. The fungus often remains undetectable in ragweed populations. This work was conducted to understand its origin and pathogenesis, a prerequisite to consider its potential as a biocontrol...
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In: Designs, Codes and Cryptography, 2013, vol. 66, no. 1-3, p. 375-390
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In: Geometriae Dedicata, 2012, vol. 157, no. 1, p. 331-338
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In: Geometriae Dedicata, 2008, vol. 134, no. 1, p. 177-196
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In: manuscripta mathematica, 2007, vol. 122, no. 3, p. 321-339
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