In: International journal of molecular sciences, 2021, vol. 22, no. 12, p. 24
Inflammation in the tumor microenvironment has been shown to promote disease progression in pancreatic ductal adenocarcinoma (PDAC); however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model of PDAC, we demonstrate that macrophages from tumor-bearing mice exhibit elevated glycolysis. Macrophage- specific deletion of Glucose Transporter 1...
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In: Diabetologia, 2015, vol. 58, no. 8, p. 1827-1835
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In: Cell and Tissue Research, 2015, vol. 359, no. 3, p. 841-851
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In: The Journal of Clinical Endocrinology & Metabolism, 2016, vol. 101, no. 8, p. 3240-3249
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In: Journal of Molecular Cell Biology, 2016, vol. 8, no. 1, p. 62-72
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In: Human reproduction update, ///-
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In: The American Journal of Clinical Nutrition, 2016, vol. 104, no. 3, p. 566-575
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In: Annals of Biomedical Engineering, 2015, vol. 43, no. 4, p. 1014-1023
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In: Pharmacology, 2020, vol. 105, no. 9–10, p. 491–504
Background: Adipose tissue inflammation occurs not only in obesity but also in aging and is mechanistically linked with age-associated diseases. Studies show that ablation of the l-arginine-metabolizing enzyme arginase-II (Arg-II) reduces adipose tissue inflammation and improves glucose tolerance in obesity. However, the role of Arg-II in aging adipose tissue inflammation is not clear....
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In: Methods in Ecology and Evolution, 2020, vol. -, no. -, p. -
raxmlGUI is a graphical user interface to RAxML, one of the most popular and widely used softwares for phylogenetic inference using maximum likelihood.Here we present raxmlGUI 2.0, a complete rewrite of the GUI which seamlessly integrates RAxML binaries for all major operating systems with an intuitive graphical front‐end to setup and run phylogenetic analyses.Our program offers automated...
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