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Università della Svizzera italiana

Impact of COVID-19 on the thyroid gland : an update

Scappaticcio, Lorenzo ; Pitoia, Fabián ; Esposito, Katherine ; Piccardo, Arnoldo ; Trimboli, Pierpaolo

In: Reviews in Endocrine and Metabolic Disorders, 2020, p. 13

Coronavirus disease 2019 (COVID-19) is the pandemic of the new millennium. COVID-19 can cause both pulmonary and systemic inflammation, potentially determining multi-organ dysfunction. Data on the relationship between COVID-19 and thyroid have been emerging, and rapidly increasing since March 2020. The thyroid gland and the virus infection with its associated inflammatory-immune responses are...

Université de Fribourg

A standard numbering scheme for class c β-lactamases

Mack, Andrew R. ; Barnes, Melissa D. ; Taracila, Magdalena A. ; Hujer, Andrea M. ; Hujer, Kristine M. ; Cabot, Gabriel ; Feldgarden, Michael ; Haft, Daniel H. ; Klimke, William ; Akker, Focco van den ; Vila, Alejandro J. ; Smania, Andrea ; Haider, Shozeb ; Papp-Wallace, Krisztina M. ; Bradford, Patricia A. ; Rossolini, Gian Maria ; Docquier, Jean-Denis ; Frère, Jean-Marie ; Galleni, Moreno ; Hanson, Nancy D. ; Oliver, Antonio ; Plésiatyz, Patrick ; Poirel, Laurent ; Nordmann, Patrice ; Palzkill, Timothy G. ; Jacoby, George A. ; Bush, Karen ; Bonomo, Robert A.

In: Antimicrobial Agents and Chemotherapy, 2020, vol. 64, no. 3, p. -

Unlike for classes A and B, a standardized amino acid numbering scheme has not been proposed for the class C (AmpC) β-lactamases, which complicates communication in the field. Here, we propose a scheme developed through a collaborative approach that considers both sequence and structure, preserves traditional numbering of catalytically important residues (Ser64, Lys67, Tyr150, and Lys315),...

Université de Fribourg

Enigmatic dinosaur precursors bridge the gap to the origin of Pterosauria

Ezcurra, Martín D. ; Nesbitt, Sterling J. ; Bronzati, Mario ; Vecchia, Fabio Marco Dalla ; Agnolin, Federico L. ; Benson, Roger B. J. ; Egli, Federico Brissón ; Cabreira, Sergio F. ; Evers, Serjoscha W. ; Gentil, Adriel R. ; Irmis, Randall B. ; Martinelli, Agustín G. ; Novas, Fernando E. ; Silva, Lúcio Roberto da ; Smith, Nathan D. ; Stocker, Michelle R. ; Turner, Alan H. ; Langer, Max C.

In: Nature, 2020, vol. 588, no. 2020-7838, p. 445–449

Pterosaurs were the first vertebrates to evolve powered flight1 and comprised one of the main evolutionary radiations in terrestrial ecosystems of the Mesozoic era (approximately 252–66 million years ago), but their origin has remained an unresolved enigma in palaeontology since the nineteenth century2,3,4. These flying reptiles have been hypothesized to be the close relatives of a wide...

Université de Fribourg

Directing single-molecule emission with dna origami-assembled optical antennas

Hübner, Kristina ; Pilo-Pais, Mauricio ; Selbach, Florian ; Liedl, Tim ; Tinnefeld, Philip ; Stefani, Fernando D. ; Acuna, Guillermo P.

In: Nano Letters, 2019, vol. 19, no. 9, p. 6629–6634

We demonstrate the capability of DNA self-assembled optical antennas to direct the emission of an individual fluorophore, which is free to rotate. DNA origami is used to fabricate optical antennas composed of two colloidal gold nanoparticles separated by a predefined gap and to place a single Cy5 fluorophore near the gap center. Although the fluorophore is able to rotate, its excitation and...

Consortium of Swiss Academic Libraries

Continuing impacts on red deer from a volcanic eruption in 2011

Flueck, Werner

In: European Journal of Wildlife Research, 2014, vol. 60, no. 4, p. 699-702

Université de Fribourg

Characterising Chordal Contact : Bo-VPG Graphs

Bonomo, Flavia ; Mazzoleni, Maria Pia ; Rean, Mariano Leonardo ; Ries, Bernard

In: Lecture Notes in Computer Science, 2018, vol. 10856, p. 89-100

A graph G is a Bo- VPG graph if it is the vertex intersection graph of horizontal and vertical paths on a grid. A graph G is a contact Bo- VPG graph if the vertices can be represented by interiorly disjoint horizontal or vertical paths on a grid and two vertices are adjacent if and only if the corresponding paths touch. In this paper, we present a minimal forbidden induced subgraph...

Université de Fribourg

On star and biclique edge-colorings

Dantas, Simone ; Groshaus, Marina ; Guedes , André ; C.S. Machado, Raphael ; Ries, Bernard ; Sasaki, Diana

In: International Transactions in Operational Research, 2017, vol. 24, p. 339-346

A biclique of G is a maximal set of vertices that induces a complete bipartite subgraph Kp,q of G with at least one edge, and a star of a graph G is a maximal set of vertices that induces a complete bipartite graph K1,q. A biclique (resp. star) edge-coloring is a coloring of the edges of a graph with no monochromatic bicliques (resp. stars). We prove that the problem of determining whether a...