In: Brain, 2016, vol. 139, no. 1, p. 39-46
|
In: PLOS genetics, 2019, vol. 15, no. 4, p. e1008069
In the peripheral nervous system (PNS) myelinating Schwann cells synthesize large amounts of myelin protein zero (P0) glycoprotein, an abundant component of peripheral nerve myelin. In humans, mutations in P0 cause the demyelinating Charcot-Marie-Tooth 1B (CMT1B) neuropathy, one of the most diffused genetic disorders of the PNS. We previously showed that several mutations, such as the...
|
In: Scientific Reports, 2019, vol. 9, no. 1, p. 10603
Forebrain glial cells - ependymal cells and astrocytes -acquire upon injury- a “reactive” phenotype associated with parvalbumin (PV) upregulation. Since free radicals, e.g. reactive oxygen species (ROS) play a role in the pathogenesis of multiple sclerosis, and that PV-upregulation in glial cells is inversely correlated with the level of oxidative stress, we hypothesized that...
|
In: Acta Neuropathologica, 2014, vol. 128, no. 2, p. 231-246
|
In: Acta Neuropathologica, 2019, vol. 137, no. 2, p. 239–257
Brain accumulation and aggregation of amyloid-β (Aβ) peptides is a critical step in the pathogenesis of Alzheimer’s disease (AD). Full-length Aβ peptides (mainly Aβ1–40 and Aβ1–42) are produced through sequential proteolytic cleavage of the amyloid precursor protein (APP) by β- and γ-secretases. However, studies of autopsy brain samples from AD patients have demonstrated that a...
|
In: Neurological Sciences, 2007, vol. 28, no. 4, p. 161-162
|
In: Journal of Molecular Neuroscience, 2008, vol. 35, no. 1, p. 91-100
|
In: European Journal of Applied Physiology, 2013, vol. 113, no. 3, p. 631-640
|
In: Pediatric Radiology, 1997, vol. 27, no. 2, p. 155-158
|
In: Diabetologia, 2005, vol. 48, no. 7, p. 1258-1263
|