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Università della Svizzera italiana

A novel UGGT1 and p97-dependent checkpoint for native ectodomains with ionizable intramembrane residue

Merulla, Jessica ; Tatiana Soldà ; Maurizio Molinari

In: Molecular biology of the cell, 2015, vol. 26, no. 8, p. 1413-1574

Only native polypeptides are released from the endoplasmic reticulum (ER) to be transported at the site of activity. Persistently misfolded proteins are retained and eventually selected for ER-associated degradation (ERAD). The paradox of a structure- based protein quality control is that functional polypeptides may be destroyed if they are architecturally unfit. This has health-threatening...

Université de Neuchâtel

Application of carbon-chlorine isotopic analysis to determine the origin and fate of chlorinated ethenes in groundwater

Badin, Alice ; Hunkeler, Daniel (Dir.) ; Schirmer, Mario (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2015.

Chlorinated ethenes are ubiquitous groundwater contaminants posing a threat to one of our main drinking water sources. Despite their spill history dating back to more than 40 years ago, these contaminants are still found in groundwater in numerous industrially developed countries due to their persistence, difficult characterisation in the subsurface and resulting challenging remediation. When...

Consortium of Swiss Academic Libraries

Glycogen reduction in non-exercising muscle depends on blood lactate concentration

Kohler, Götz ; Boutellier, Urs

In: European Journal of Applied Physiology, 2004, vol. 92, no. 4-5, p. 548-554