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Consortium of Swiss Academic Libraries

Population pharmacokinetic analysis of elvitegravir and cobicistat in HIV-1-infected individuals

Barceló, Catalina ; Gaspar, Frédéric ; Aouri, Manel ; Panchaud, Alice ; Rotger, Margalida ; Guidi, Monia ; Cavassini, Matthias ; Buclin, Thierry ; Decosterd, Laurent A. ; Csajka, Chantal ; Aubert, V. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Braun, DL ; Bucher, HC ; Burton-Jeangros, C. ; Calmy, A. ; Cavassini, M. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, CA ; Gorgievski, M. ; Günthard, H. ; Haerry, D. ; Hasse, B. ; Hirsch, HH ; Hoffmann, M. ; Hösli, I. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Marzolini, C. ; Metzner, K. ; Müller, N. ; Nadal, D. ; Nicca, D. ; Pantaleo, G. ; Rauch, A. ; Regenass, S. ; Rudin, C. ; Schöni-Affolter, F. ; Schmid, P. ; Speck, R. ; Stöckle, M. ; Tarr, P. ; Trkola, A. ; Vernazza, P. ; Weber, R. ; Yerly, S. ; Aubert, V. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Braun, DL ; Bucher, HC ; Burton-Jeangros, C. ; Calmy, A. ; Cavassini, M. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, CA ; Gorgievski, M. ; Günthard, H. ; Haerry, D. ; Hasse, B. ; Hirsch, HH ; Hoffmann, M. ; Hösli, I. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Marzolini, C. ; Metzner, K. ; Müller, N. ; Nadal, D. ; Nicca, D. ; Pantaleo, G. ; Rauch, A. ; Regenass, S. ; Rudin, C. ; Schöni-Affolter, F. ; Schmid, P. ; Speck, R. ; Stöckle, M. ; Tarr, P. ; Trkola, A. ; Vernazza, P. ; Weber, R. ; Yerly, S.

In: Journal of Antimicrobial Chemotherapy, 2016, vol. 71, no. 7, p. 1933-1942

Università della Svizzera italiana

An MVA vector expressing HIV-1 envelope under the control of a potent vaccinia virus promoter as a promising strategy in HIV/AIDS vaccine design

Pérez, Patricia ; Marín, María Q. ; Lázaro-Frías, Adrián ; Sorzano, Carlos Óscar S. ; Di Pilato, Mauro ; Gómez, Carmen E. ; Esteban, Mariano ; García-Arriaza, Juan

In: Vaccines, 2019, vol. 7, no. 4, p. 208

Highly attenuated poxviral vectors, such as modified vaccinia virus ankara (MVA), are promising vaccine candidates against several infectious diseases. One of the approaches developed to enhance the immunogenicity of poxvirus vectors is increasing the promoter strength and accelerating during infection production levels of heterologous antigens. Here, we have generated and characterized the ...

Università della Svizzera italiana

Proteome-wide analysis of HIV-specific naive and memory CD4+ T cells in unexposed blood donors

Campion, Suzanne L. ; Brodie, Tess M. ; Fischer, William ; Korber, Bette T. ; Rossetti, Astrea ; Goonetilleke, Nilu ; McMichael, Andrew J. ; Sallusto, Federica

In: Journal of experimental medicine, 2014, vol. 211, no. 7, p. 1273-1280

The preexisting HIV-1–specific T cell repertoire must influence both the immunodominance of T cells after infection and immunogenicity of vaccines. We directly compared two methods for measuring the preexisting CD4+ T cell repertoire in healthy HIV-1–negative volunteers, the HLA-peptide tetramer enrichment and T cell library technique, and show high concordance (r = 0.989). Using the...

Consortium of Swiss Academic Libraries

Efavirenz-induced urolithiasis

Wirth, G. ; Teuscher, J. ; Graf, J. ; Iselin, C.

In: Urological Research, 2006, vol. 34, no. 4, p. 288-289