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Université de Fribourg

CD47 promotes age-associated deterioration in angiogenesis, blood flow and glucose homeostasis

Ghimire, Kedar ; Li, Yao ; Chiba, Takuto ; Julovi, Sohel M. ; Li, Jennifer ; Ross, Mark A. ; Straub, Adam C. ; O’Connell, Philip J. ; Rüegg, Curzio ; Pagano, Patrick J. ; Isenberg, Jeffrey S. ; Rogers, Natasha M.

In: Cells, 2020, vol. 9, no. 7, p. 1695

The aged population is currently at its highest level in human history and is expected to increase further in the coming years. In humans, aging is accompanied by impaired angiogenesis, diminished blood flow and altered metabolism, among others. A cellular mechanism that impinges upon these manifestations of aging can be a suitable target for therapeutic intervention. Here we identify cell...

Université de Fribourg

Tunable 2D binary colloidal alloys for soft nanotemplating

Fernández-Rodríguez, Miguel Ángel ; Elnathan, Roey ; Ditcovski, Ran ; Grillo, Fabio ; Conley, Gaurasundar Marc ; Timpu, Flavia ; Rauh, Astrid ; Geisel, Karen ; Ellenbogen, Tal ; Grange, Rachel ; Scheffold, Frank ; Karg, Matthias ; Richtering, Walter ; Voelcker, Nicolas H. ; Isa, Lucio

In: Nanoscale, 2018, vol. 10, no. 47, p. 22189–22195

The realization of non-close-packed nanoscale patterns with multiple feature sizes and length scales via colloidal self-assembly is a highly challenging task. We demonstrate here the creation of a variety of tunable particle arrays by harnessing the sequential self-assembly and deposition of two differently sized microgel particles at the fluid–fluid interface. The two-step process is...