Refine my results

Document type

Specific Collection

Language

Université de Fribourg

Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance

Stolp, Bettina ; Thelen, Flavian ; Ficht, Xenia ; Altenburger, Lukas M. ; Ruef, Nora ; Inavalli, V. V. G. Krishna ; Germann, Philipp ; Page, Nicolas ; Moalli, Federica ; Raimondi, Andrea ; Keyser, Kirsten A. ; Jafari, S. Morteza Seyed ; Barone, Francesca ; Dettmer, Matthias S. ; Merkler, Doron ; Iannacone, Matteo ; Sharpe, James ; Schlapbach, Christoph ; Fackler, Oliver T. ; Nägerl, U. Valentin ; Stein, Jens V.

In: Science Immunology, 2020, vol. 5, no. 46, p. eaaz4371

It is well established that tissue macrophages and tissue-resident memory CD8+ T cells (TRM) play important roles for pathogen sensing and rapid protection of barrier tissues. In contrast, the mechanisms by which these two cell types cooperate for homeostatic organ surveillance after clearance of infections is poorly understood. Here, we used intravital imaging to show that TRM dynamically...

Università della Svizzera italiana

Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice

Hauber, Ilona ; Hofmann-Sieber, Helga ; Chemnitz, Jan ; Dubrau, Danilo ; Chusainow, Janet ; Stucka, Rolf ; Hartjen, Philip ; Schambach, Axel ; Ziegler, Patrick ; Hackmann, Karl ; Schröck, Evelin ; Schumacher, Udo ; Lindner, Christoph ; Grundhoff, Adam ; Baum, Christopher ; Manz, Markus G. ; Buchholz, Frank ; Hauber, Joachim

In: Plos pathogens, 2013, vol. 9, no. 9, p. e1003587

Stable integration of HIV proviral DNA into host cell chromosomes, a hallmark and essential feature of the retroviral life cycle, establishes the infection permanently. Current antiretroviral combination drug therapy cannot cure HIV infection. However, expressing an engineered HIV-1 long terminal repeat (LTR) site-specific recombinase (Tre), shown to excise integrated proviral DNA in vitro,...

Consortium of Swiss Academic Libraries

The effects of parental leave extension on training for young women

Puhani, Patrick ; Sonderhof, Katja

In: Journal of Population Economics, 2011, vol. 24, no. 2, p. 731-760

Consortium of Swiss Academic Libraries

Min- and Max-Entropy in Infinite Dimensions

Furrer, Fabian ; Åberg, Johan ; Renner, Renato

In: Communications in Mathematical Physics, 2011, vol. 306, no. 1, p. 165-186