In: American Journal of Epidemiology, 2018, vol. 187, no. 8, p. 1714-1720
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In: Glycobiology, 2017, vol. 27, no. 6, p. 525-535
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In: Glycobiology, 2018, vol. 28, no. 9, p. 638-639
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In: Glycobiology, 2016, vol. 26, no. 2, p. 111-128
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In: Angewandte Chemie International Edition, 2020, vol. 60, no. 2, p. 904-909
Some marine plankton called dinoflagellates emit light in response to the movement of surrounding water, resulting in a phenomenon called milky seas or sea sparkle. The underlying concept, a shear-stress induced permeabilisation of biocatalytic reaction compartments, is transferred to polymer-based nanoreactors. Amphiphilic block copolymers that carry nucleobases in their hydrophobic block...
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In: PLOS ONE, 2020, vol. 15, no. 9, p. e0238134
Malaria is a life-threatening disease, caused by Apicomplexan parasites of the Plasmodium genus. The Anopheles mosquito is necessary for the sexual replication of these parasites and for their transmission to vertebrate hosts, including humans. Imaging of the parasite within the insect vector has been attempted using multiple microscopy methods, most of which are hampered by the presence of...
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In: Scientific Reports, 2020, vol. 10, no. 1, p. 8268
Sphingosine-1-phosphate is a signaling molecule involved in the control of cell migration, differentiation, survival and other physiological processes. This sphingolipid metabolite can be degraded by the action of sphingosine-1-phosphate lyase (SPL) to form hexadecenal and ethanolamine phosphate. The importance of SPL-mediated ethanolamine phosphate formation has been characterized in only...
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In: Physics Reports, 2020, vol. 846, p. 1–66
Biological entities are involved in intricate and complex interactions, in which uncovering the biological information from the network concepts are of great significance. Benefiting from the advances of network science and high-throughput biomedical technologies, studying the biological systems from network biology has attracted much attention in recent years, and networks have long been...
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In: EMBO molecular medicine, 2016, vol. 8, no. 4, p. 407-421
Currently available rabies post‐exposure prophylaxis (PEP) for use in humans includes equine or human rabies immunoglobulins (RIG). The replacement of RIG with an equally or more potent and safer product is strongly encouraged due to the high costs and limited availability of existing RIG. In this study, we identified two broadly neutralizing human monoclonal antibodies that represent a...
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In: PLOS Neglected Tropical Diseases, 2019, vol. 13, no. 4, p. e0007293
Salmonella organisms are classified into typhoidal Salmonella (causing enteric fever) and non-typhoidal Salmonella (NTS) (causing infections other than enteric fever). Apart from causing other infections, NTS causes blood-stream infection (bacteremia and septicemia). NTS blood stream infection (NTS-BI) is considered to be an emerging and neglected tropical disease in Africa. It causes a very...
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