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Università della Svizzera italiana

Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface

Di Zenzo, Giovanni ; Di Lullo, Giulia ; Corti, Davide ; Calabresi, Valentina ; Sinistro, Anna ; Vanzetta, Fabrizia ; Didona, Biagio ; Cianchini, Giuseppe ; Hertl, Michael ; Eming, Rudiger ; Amagai, Masayuki ; Ohyama, Bungo ; Hashimoto, Takashi ; Sloostra, Jerry ; Sallusto, Federica ; Zambruno, Giovanna ; Lanzavecchia, Antonio

In: The journal of clinical investigation, 2012, vol. 122, no. 10, p. 3781-3790

Pemphigus vulgaris (PV) is an autoimmune blistering disease of skin and mucous membranes caused by autoantibodies to the desmoglein (DSG) family proteins DSG3 and DSG1, leading to loss of keratinocyte cell adhesion. To learn more about pathogenic PV autoantibodies, we isolated 15 IgG antibodies specific for DSG3 from 2 PV patients. Three antibodies disrupted keratinocyte monolayers in vitro,...

Public access from Nov 1, 2019
Consortium of Swiss Academic Libraries

Posterior auricular artery as an alternative donor vessel for extracranial-intracranial bypass surgery

Germans, Menno ; Regli, Luca

In: Acta Neurochirurgica, 2014, vol. 156, no. 11, p. 2095-2101

Consortium of Swiss Academic Libraries

Postmortem imaging of sudden cardiac death

Michaud, Katarzyna ; Grabherr, Silke ; Jackowski, Christian ; Bollmann, Marc ; Doenz, Franceso ; Mangin, Patrice

In: International Journal of Legal Medicine, 2014, vol. 128, no. 1, p. 127-137

Consortium of Swiss Academic Libraries

Cardiac hybrid imaging

Gaemperli, Oliver ; Kaufmann, Philipp ; Alkadhi, Hatem

In: European Journal of Nuclear Medicine and Molecular Imaging, 2014, vol. 41, p. 91-103

Consortium of Swiss Academic Libraries

Immunological aspects of atherosclerosis

Garrido-Urbani, S. ; Meguenani, M. ; Montecucco, F. ; Imhof, B.

In: Seminars in Immunopathology, 2014, vol. 36, no. 1, p. 73-91