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Università della Svizzera italiana

A novel prostate cell type-specific gene signature to interrogate prostate tumor differentiation status and monitor therapeutic response (running title: Phenotypic classification of prostate tumors)

Mapelli, Sarah N. ; Albino, Domenico ; Mello-Grand, Maurizia ; Shinde, Dheeraj ; Scimeca, Manuel ; Bonfiglio, Rita ; Bonanno, Elena ; Chiorino, Giovanna ; Garcia-Escudero, Ramon ; Catapano, Carlo V. ; Carbone, Giuseppina M.

In: Cancers, 2020, vol. 12, no. 1, p. 23 p

In this study, we extracted prostate cell-specific gene sets (metagenes) to define the epithelial differentiation status of prostate cancers and, using a deconvolution-based strategy, interrogated thousands of primary and metastatic tumors in public gene profiling datasets. We identified a subgroup of primary prostate tumors with low luminal epithelial enrichment (LumElow). LumElow tumors were...

Université de Fribourg

Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer

Lan, Qiang ; Peyvandi, Sanam ; Duffey, Nathalie ; Huang, Yu-Ting ; Barras, David ; Held, Werner ; Richard, François ; Delorenzi, Mauro ; Sotiriou, Christos ; Desmedt, Christine ; Lorusso, Girieca ; Rüegg, Curzio

In: Oncogene, 2019, vol. 38, no. 15, p. 2814–2829

Neoadjuvant and adjuvant chemotherapies provide survival benefits to breast cancer patients, in particular in estrogen receptor negative (ER−) cancers, by reducing rates of recurrences. It is assumed that the benefits of (neo)adjuvant chemotherapy are due to the killing of disseminated, residual cancer cells, however, there is no formal evidence for it. Here, we provide experimental...

Consortium of Swiss Academic Libraries

The European Modern Pollen Database (EMPD) project

Davis, Basil ; Zanon, Marco ; Collins, Pamella ; Mauri, Achille ; Bakker, Johan ; Barboni, Doris ; Barthelmes, Alexandra ; Beaudouin, Celia ; Bjune, Anne ; Bozilova, Elissaveta ; Bradshaw, Richard ; Brayshay, Barbara ; Brewer, Simon ; Brugiapaglia, Elisabetta ; Bunting, Jane ; Connor, Simon ; de Beaulieu, Jacques-Louis ; Edwards, Kevin ; Ejarque, Ana ; Fall, Patricia ; Florenzano, Assunta ; Fyfe, Ralph ; Galop, Didier ; Giardini, Marco ; Giesecke, Thomas ; Grant, Michael ; Guiot, Jöel ; Jahns, Susanne ; Jankovská, Vlasta ; Juggins, Stephen ; Kahrmann, Marina ; Karpińska-Kołaczek, Monika ; Kołaczek, Piotr ; Kühl, Norbert ; Kuneš, Petr ; Lapteva, Elena ; Leroy, Suzanne ; Leydet, Michelle ; Guiot, José ; López Sáez, José ; Masi, Alessia ; Matthias, Isabelle ; Mazier, Florence ; Meltsov, Vivika ; Mercuri, Anna ; Miras, Yannick ; Mitchell, Fraser ; Morris, Jesse ; Naughton, Filipa ; Nielsen, Anne ; Novenko, Elena ; Odgaard, Bent ; Ortu, Elena ; Overballe-Petersen, Mette ; Pardoe, Heather ; Peglar, Silvia ; Pidek, Irena ; Sadori, Laura ; Seppä, Heikki ; Severova, Elena ; Shaw, Helen ; Święta-Musznicka, Joanna ; Theuerkauf, Martin ; Tonkov, Spassimir ; Veski, Siim ; van der Knaap, W. ; van Leeuwen, Jacqueline ; Woodbridge, Jessie ; Zimny, Marcelina ; Kaplan, Jed

In: Vegetation History and Archaeobotany, 2013, vol. 22, no. 6, p. 521-530