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Consortium of Swiss Academic Libraries

The role of the acquired immune response in systemic sclerosis

Chizzolini, Carlo ; Boin, Francesco

In: Seminars in Immunopathology, 2015, vol. 37, no. 5, p. 519-528

Université de Fribourg

Nonparametric estimation of natural direct and indirect effects based on inverse probability weighting

Huber, Martin ; Yu-Chin, Hsu ; Tsung-Chih, Lai

In: Journal of Econometric Methods, 2019, vol. 8, no. 1, p. 1-20

Using a sequential conditional independence assumption, this paper discusses fully nonparametric estimation of natural direct and indirect causal effects in causal mediation analysis based on inverse probability weighting. We propose estimators of the average indirect effect of a binary treatment, which operates through intermediate variables (or mediators) on the causal path between the...

Consortium of Swiss Academic Libraries

Cholesterol Transport and Regulation in the Mammary Gland

Ontsouka, Edgar ; Albrecht, Christiane

In: Journal of Mammary Gland Biology and Neoplasia, 2014, vol. 19, no. 1, p. 43-58

Université de Fribourg

Constitutional absence of epithelial integrin α3 impacts the composition of the cellular microenvironment of ILNEB keratinocytes

He, Yinghong ; Thriene, Kerstin ; Boerries, Melanie ; Hausser, Ingrid ; Franzke, Claus-Werner ; Busch, Hauke ; Dengjel, Jörn ; Has, Cristina

In: Matrix Biology, 2018, vol. 74, p. 62-76

Integrin α3β1, a major epidermal adhesion receptor is critical for organization of the basement membrane during development and wound healing. Integrin α3 deficiency leads to interstitial lung disease, nephrotic syndrome and epidermolysis bullosa (ILNEB), an autosomal recessive multiorgan disease characterized by basement membrane abnormalities in skin, lung and kidney. The pathogenetic...

Université de Fribourg

Three-dimensional cell culture conditions affect the proteome of cancer-associated fibroblasts

Tölle, Regine C. ; Gaggioli, Cedric ; Dengjel, Jörn

In: Journal of Proteome Research, 2018, vol. 17, no. 8, p. 2780–2789

In vitro cell culture systems are an invaluable tool for cell biological research to study molecular pathways and to characterize processes critical in human pathophysiology. However, the experimental conditions in two-dimensional (2D) cell cultures often differ substantially from the in vivo situation, which continuously raises concerns about the reliability and conferrability of the...

Consortium of Swiss Academic Libraries

The Mammary Gland Vasculature Revisited

Andres, Anne-Catherine ; Djonov, Valentin

In: Journal of Mammary Gland Biology and Neoplasia, 2010, vol. 15, no. 3, p. 319-328

Consortium of Swiss Academic Libraries

Alveolar and Lactogenic Differentiation

Brisken, Cathrin ; Rajaram, Renuga

In: Journal of Mammary Gland Biology and Neoplasia, 2006, vol. 11, no. 3-4, p. 239-248