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Università della Svizzera italiana

A novel prostate cell type-specific gene signature to interrogate prostate tumor differentiation status and monitor therapeutic response (running title: Phenotypic classification of prostate tumors)

Mapelli, Sarah N. ; Albino, Domenico ; Mello-Grand, Maurizia ; Shinde, Dheeraj ; Scimeca, Manuel ; Bonfiglio, Rita ; Bonanno, Elena ; Chiorino, Giovanna ; Garcia-Escudero, Ramon ; Catapano, Carlo V. ; Carbone, Giuseppina M.

In: Cancers, 2020, vol. 12, no. 1, p. 23 p

In this study, we extracted prostate cell-specific gene sets (metagenes) to define the epithelial differentiation status of prostate cancers and, using a deconvolution-based strategy, interrogated thousands of primary and metastatic tumors in public gene profiling datasets. We identified a subgroup of primary prostate tumors with low luminal epithelial enrichment (LumElow). LumElow tumors were...

Université de Fribourg

Simple assessment of height and length of flight in complex gymnastic skills: validity and reliability of a two-dimensional video analysis method

Schärer, Christoph ; Siebenthal, Luca von ; Lomax, Ishbel ; Gross, Micah ; Taube, Wolfgang ; Hübner, Klaus

In: Applied Sciences, 2019, vol. 9, no. 19, p. 3975

In artistic gymnastics, the possibility of using 2D video analysis to measure the peak height (hpeak) and length of flight (L) during routine training in order to monitor the execution and development of difficult elements is intriguing. However, the validity and reliability of such measurements remain unclear. Therefore, in this study, the hpeak and L of 38 vaults, performed by top-level...

Université de Fribourg

No evidence that frontal optical flow affects perceived locomotor speed and locomotor biomechanics when running on a treadmill

Caramenti, Martina ; Lafortuna, Claudio L. ; Mugellini, Elena ; Khaled, Omar Abou ; Bresciani, Jean-Pierre ; Dubois, Amandine

In: Applied Sciences, 2019, vol. 9, no. 21, p. 4589

We investigated how the presentation and the manipulation of an optical flow while running on a treadmill affect perceived locomotor speed (Experiment 1) and gait parameters (Experiment 2). In Experiment 1, 12 healthy participants were instructed to run at an imposed speed and to focus on their sensorimotor sensations to be able to reproduce this running speed later. After a pause, they had...

Interkantonale Hochschule für Heilpädagogik Zürich HfH

Utility of Feedback Has a Greater Impact on Learning than Ease of Decoding

Dainton, Chelsea ; Winstone, Naomi ; Klaver, Peter ; Opitz, Bertram

In: Mind, Brain, and Education, 2019, p. 1-7

While feedback is a key facilitator of learning, researchers have yet to determine the ideal feedback process for optimal performance in learners. The current study investigates the combined effects of ease of decoding, and utility of feedback during learning. Accuracy and rate of learning were recorded alongside changes to the feedback related negativity (FRN), an event‐related potential...

Université de Fribourg

Regular physical activity modulates perceived visual speed when running in treadmill-mediated virtual environments

Caramenti, Martina ; Lafortuna, Claudio L. ; Mugellini, Elena ; Khaled, Omar Abou ; Bresciani, Jean-Pierre ; Dubois, Amandine

In: PLOS ONE, 2019, vol. 14, no. 6, p. e0219017

In virtual reality, visual speed is usually underestimated relative to locomotor speed. Here we investigated how physical activity and fitness affect perceived visual speed when running in a treadmill-mediated virtual environment. Thirty healthy participants (ten sedentary individuals, ten team sport players and ten expert runners) ran on a treadmill at two different speeds (8, 12km/h) in...

Haute école de santé Genève

Programme de course à pied avec feedback visuel : que est l'intérêt sur le taux de mise en charge au sol chez les coureurs adultes : travail de Bachelor

Streit, Romain ; Maire, Sophie ; Gard, Suzanne (Dir.)

Mémoire de bachelor : Haute école de santé Genève, 2019.

Introduction : Running is a physical activity commonly practiced around the world but is also in the top ten sports with the highest incidence of injuries. The impact loading of the foot on the ground has been correlated to an increased risk of developing tibial stress fractures or recurrences of these. Therefore, an approach consisting of a gait retraining program with visual feedback could be...

Université de Neuchâtel

Evolution of the "Castanea sativa" - "Dryocosmus kuriphilus" - "Torymus sinensis" - system in southern Switzerland

Gehring, Eric ; Aebi, Alexandre (Dir.) ; Conedera, Marco (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

The arrival of new organisms that may potentially become harmful for people and ecosystems has become a world-wide daily concern to the point that in Switzerland about 800 established alien species exist, of which at least 107 are considered invasive. A possible way to control such pests is by importing and releasing natural enemies from their countries of origin, letting them to act as so-called...

Université de Fribourg

Effect of different loading conditions on running mechanics at different velocities

Carretero-Navarro, Germán ; Márquez, Gonzalo ; Cherubini, Doménico ; Taube, Wolfgang

In: European Journal of Sport Science, 2019, vol. 19, no. 5, p. 595–602

Weighted vests are widely used to improve running economy and performance. However, it is not well-studied how running mechanics are adapted to counteract the higher peak vertical ground reaction forces (Fpeak) while running with such a device. Therefore, the present study aimed to investigate the effects of different loading conditions on running mechanics at different velocities. Thirteen...