In: Sleep, 2016, vol. 39, no. 12, p. 2125-2132
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In: Cerebral Cortex, 2017, vol. 27, no. 8, p. 4048-4059
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In: Somnologie - Schlafforschung und Schlafmedizin, 2015, vol. 19, no. 2, p. 133-140
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In: Psychonomic Bulletin & Review, 2015, vol. 22, no. 1, p. 274-280
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In: BioEssays, 2019, vol. 41, no. 8, p. 1900045
Consolidation of long‐term memory is a highly and precisely regulated multistep process. The transcription regulator cAMP response element‐binding protein (CREB) plays a key role in initiating memory consolidation. With time processing, first the cofactors are changed and, secondly, CREB gets dispensable. This ultimately changes the expressed gene program to genes required to maintain the...
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In: Psychological Research, 2014, vol. 78, no. 6, p. 803-820
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In: Current Neurology and Neuroscience Reports, 2014, vol. 14, no. 2, p. 1-10
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In: Frontiers in Cellular Neuroscience, 2019, vol. 13, p. -
Chromatin immunoprecipitation (ChIP) is an assay developed in order to define the dynamic nature of transcription processes. This method has been widely employed to identify methylated and acetylated DNA sequences in a variety of organs both in animals and humans. Nevertheless, this technique is significantly less employed to study transcriptional targets of specific nuclear signaling factors...
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In: Neurobiology of Aging, 2019, vol. 76, p. 80–95
Olfaction declines with aging and appears to be a prodromal sign of cognitive decline in progressive neurodegenerative diseases. Nevertheless, very little is known about the pathophysiological changes underlying smell loss that may reflect early network dysfunction. A cross-sectional histoanatomical study was conducted on postmortem olfactory nerves of patients with increasing severity of...
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In: Journal of Experimental Neuroscience, 2018, vol. 12, p. -
Major depressive disorder (MDD) is one of the most common neuropsychiatric disorders affecting over one-fifth of the population worldwide. Owing to our limited understanding of the pathophysiology of MDD, the quest for finding novel antidepressant drug targets is severely impeded. Monoamine hypothesis of MDD provides a robust theoretical framework, forming the core of a large jigsaw puzzle, ...
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