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Université de Fribourg

Ecological Monitoring and Management App (EMMA) for Older Adults With Chronic Pain: Protocol for a Design and Feasibility Study

Ledermann, Katharina ; Abou Khaled, Omar ; Caon, Maurizio ; Berger, Thomas ; Chabwine, Joelle ; Martin-Soelch, Chantal

In: JMIR Research Protocols

Background: Chronic pain is a complex problem for many older adults that affects both physical functioning and psychological well-being. Mobile health (mHealth) technologies have shown promise in supporting older persons in managing chronic conditions. Cognitive behavior therapy (CBT) is recommended for older people with chronic pain. However, online treatment programs for chronic pain are...

Université de Fribourg

Everybody Knows that There Is Something Odd About Ad Populum Arguments

Herman, Thierry ; Oswald, Steve

In: The Language of Argumentation, 2021, p. 305-323

In the wake of research on linguistic resources of argumentation (Doury, 2018; van Eemeren Houtlosser, & Snoeck Henkemans, 2007), this chapter considers the argumentative nature and rhetorical potential of the expression “everyone/everybody knows P”, which is likely to be used to fulfil a justificatory purpose in appeals to majority in the form of ad populum arguments (Godden, 2008). In...

Université de Fribourg

Nicole Oresme à la Faculté des Arts de Paris: Les Questions sur les Météorologiques

Panzica, Aurora

In: Archives d’histoire doctrinale et littéraire du Moyen Âge, 2017, vol. 84, p. 7–89

"This paper deals with Nicole Oresme's Questions on Meteorology, one of the few unedited works of this philosopher. The first part concerns the manuscript tradition of this commentary, and particularly the discovery of an earlier redaction, which differs considerably from the currently known one. Subsequently, an attempt will be made to clarify the chronological position of these two...

Université de Fribourg

A Framework for Separating Individual-Level Treatment Effects From Spillover Effects

Huber, Martin ; Steinmayr, Andreas

In: Journal of Business & Economic Statistics, 2019, p. 1-15

This article suggests a causal framework for separating individual-level treatment effects and spillover effects such as general equilibrium, interference, or interaction effects related to treatment distribution. We relax the stable unit treatment value assumption assuming away treatment-dependent interaction between study participants and permit spillover effects within aggregates, for...

Université de Fribourg

New paroxyclaenid mammals from the early Eocene of the Paris Basin (France) shed light on the origin and evolution of these endemic European cimolestans

Solé, Floréal ; Plateau, Olivia ; Le Verger, Kévin ; Phélizon, Alain

In: Journal of Systematic Palaeontology, 2019, vol. 17, no. 20, p. 1711–1743

We present new species of an enigmatic family of mammals, which is endemic to Europe, the Paroxyclaenidae: Merialus bruneti sp. nov., Fratrodon tresvauxi gen. et sp. nov., Paraspaniella gunnelli gen. et sp. nov., and Sororodon tresvauxae gen. et sp. nov. The fossils described come from six localities of the Ypresian of the Paris Basin (France): Pourcy (MP7), Mutigny, Avenay, Condé-en-Brie...

Università della Svizzera italiana

TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut

Romagnani, Andrea ; Vettore, Valentina ; Rezzonico-Jost, Tanja ; Hampe, Sarah ; Rottoli, Elsa ; Nadolni, Wiebke ; Perotti, Michela ; Meier, Melanie A. ; Hermanns, Constanze ; Geiger, Sheila ; Wennemuth, Gunther ; Recordati, Camilla ; Matsushita, Masayuki ; Muehlich, Susanne ; Proietti, Michele ; Chubanov, Vladimir ; Gudermann, Thomas ; Grassi, Fabio ; Zierler, Susanna

In: Nature communications, 2017, vol. 8, p. 1917

The melastatin-like transient-receptor-potential-7 protein (TRPM7), harbouring a cation channel and a serine/threonine kinase, has been implicated in thymopoiesis and cytokine expression. Here we show, by analysing TRPM7 kinase-dead mutant (Trpm7 R/R) mice, that the enzymatic activity of the receptor is not essential for thymopoiesis, but is required for CD103 transcription and gut-homing of ...

Haute école de gestion de Genève

A response to the Paris Agreement : What types of measures should be implemented in Geneva to leverage the potential of the private sector in mitigating environmental impact?

Joly, Matthias ; Matile, Laurent (Dir.)

Mémoire de bachelor : Haute école de gestion de Genève, 2018 ; TDIBM 36.

Since the signature of the Paris Agreement, a crucial role has been recognized for subnational and non-state actors to take part in the mitigation efforts against global warming. Cities have a significant responsibility to implement ambitious measures, especially toward the inclusion of the private sector in climate action, for States to be able to achieve the objectives of the treaty. This...

Université de Fribourg

Numerical reconstructions of the flow and basal conditions of the Rhine glacier, European Central Alps, at the Last Glacial Maximum

Cohen, Denis ; Gillet-Chaulet, Fabien ; Haeberli, Wilfried ; Machguth, Horst ; Fischer, Urs H.

In: The Cryosphere, 2018, vol. 12, no. 8, p. 2515–2544

At the Last Glacial Maximum (LGM), the Rhine glacier in the Swiss Alps covered an area of about 16000km2. As part of an integrative study about the safety of repositories for radioactive waste under ice age conditions in Switzerland, we modeled the Rhine glacier using a thermodynamically coupled three-dimensional, transient Stokes flow and heat transport model down to a horizontal resolution...