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Haute Ecole d'Ingénierie

Miniaturized Doppler radar sensor for non-contact vital sign detection

Balle, Marcel ; Andersson, Alexandra (Dir.)

Mémoire de bachelor : Haute Ecole d'Ingénierie, 2018.

Non-contact vital sign detection based on Doppler radar systems presents several advantages in bio-medical and healthcare applications. Many research efforts have been proposed in this field to obtain accuracy and effectiveness for reliable wireless bio-signal detection. However front-end architectures, demodulation algorithms and signal processing methods can be further improved to retrieve...

Université de Fribourg

Do invasive alien plants differ from non-invasives in dominance and nitrogen uptake in response to variation of abiotic and biotic environments under global anthropogenic change?

Liu, Yuan-Yuan ; Sun, Yan ; Müller-Schärer, Heinz ; Yan, Rong ; Zhou, Zhi-Xiang ; Wang, Yong-Jian ; Yu, Fei-Hai

In: Science of The Total Environment, 2019, vol. 672, p. 634–642

Plant invasion is the outcome of complicated interactions of both biotic and abiotic environments (i.e. eutrophication and human-induced propagules) under global anthropogenic change. Here, we want to know why some alien clonal plant species become invasive and others do not in the introduced range with variations of both abiotic and biotic environments under global anthropogenic change.We...

Université de Fribourg

Targeting GATA transcription factors – a novel strategy for anti-aging interventions?

Zimmermann, Andreas ; Kainz, Katharina ; Hofer, Sebastian J. ; Bauer, Maria A. ; Schroeder, Sabrina ; Dengjel, Jörn ; Pietrocola, Federico ; Kepp, Oliver ; Ruckenstuhl, Christoph ; Eisenberg, Tobias ; Sigrist, Stephan J. ; Madeo, Frank ; Kroemer, Guido ; Carmona-Gutierrez, Didac

In: Microbial Cell, 2019, vol. 6, no. 5, p. 212–216

GATA transcription factors (TFs) constitute a conserved family of zinc-finger TFs that fulfill diverse functions across eukaryotes. Accumulating evidence suggests that GATA TFs also play a role in lifespan regulation. In a recent study, we identified a natural polyphenol, 4,4’-dimethoxychalcone (DMC), that extends lifespan depending on reduced activity of distinct GATA TFs. Prolonged...

Università della Svizzera italiana

Computational docking of antibody-antigen complexes, opportunities and pitfalls illustrated by influenza hemagglutinin

Pedotti, Mattia ; Simonelli, Luca ; Livoti, Elsa ; Varani, Luca

In: International journal of molecular sciences, 2011, vol. 12, no. 1, p. 226-251

Antibodies play an increasingly important role in both basic research and the pharmaceutical industry. Since their efficiency depends, in ultimate analysis, on their atomic interactions with an antigen, studying such interactions is important to understand how they function and, in the long run, to design new molecules with desired properties. Computational docking, the process of predicting...

Università della Svizzera italiana

Redox-mediated mechanisms fuel monocyte responses to CXCL12/HMGB1 in active rheumatoid arthritis

Cecchinato, Valentina ; D'Agostino, Gianluca ; Raeli, Lorenzo ; Nerviani, Alessandra ; Schiraldi, Milena ; Danelon, Gabriela ; Manzo, Antonio ; Thelen, Marcus ; Ciurea, Adrian ; Bianchi, Marco E. ; Rubartelli, Anna ; Pitzalis, Costantino ; Uguccioni, Mariagrazia

In: Frontiers in immunology, 2018, vol. 9, p. 2118

Chemokine synergy-inducing molecules are emerging as regulating factors in cell migration. The alarmin HMGB1, in its reduced form, can complex with CXCL12 enhancing its activity on monocytes via the chemokine receptor CXCR4, while the form containing a disulfide bond, by binding to TLR2 or TLR4, initiates a cascade of events leading to production of cytokines and chemokines. So far, the...

Public access from Sep 1, 2019
Consortium of Swiss Academic Libraries

Complex national sampling design for long-term monitoring of protected dry grasslands in Switzerland

Tillé, Yves ; Ecker, Klaus

In: Environmental and Ecological Statistics, 2014, vol. 21, no. 3, p. 453-476

Consortium of Swiss Academic Libraries

Hepatic glucose sensing and integrative pathways in the liver

Oosterveer, Maaike ; Schoonjans, Kristina

In: Cellular and Molecular Life Sciences, 2014, vol. 71, no. 8, p. 1453-1467

Consortium of Swiss Academic Libraries

Radiometric Active Indoor Imaging in the W-Band

Canavero, M. ; Murk, A. ; Mätzler, C. ; Nötel, D. ; Huck, Johann

In: Journal of Infrared, Millimeter, and Terahertz Waves, 2014, vol. 35, no. 2, p. 218-241