In: Journal of Paleolimnology, 2015, vol. 53, no. 2, p. 233-250
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In: Frontiers in Physiology, 2020, vol. 11, p. -
Endogenous circadian rhythms are biological processes generated by an internal body clock. They are self-sustaining, and they govern biochemical and physiological processes. However, circadian rhythms are influenced by many external stimuli to reprogram the phase in response to environmental change. Through their adaptability to environmental changes, they synchronize physiological responses...
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In: Scientific Reports, 2020, vol. 10, no. 1, p. 2752
Organisms possess an endogenous molecular clock which enables them to adapt to environmental rhythms and to synchronize their metabolism and behavior accordingly. Circadian rhythms govern daily oscillations in numerous physiological processes, and the underlying molecular components have been extensively described from fruit flies to mammals. Drosophila larvae have relatively simple nervous...
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In: Journal of Molecular Biology, 2020, vol. 432, no. 12, p. 3714–3721
The circadian system consists of individual cellular clocks. It organizes and synchronizes biochemical and physiological processes in order to optimally adapt an organism to its environment. This requires that the circadian system is responsive to environmental cues, which contain information about geophysical time (e.g., light), and allows an organism to predict daily recurring events....
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In: eLife, 2019, vol. 8, p. e50925
Circadian oscillations emerge from transcriptional and post-translational feedback loops. An important step in generating rhythmicity is the translocation of clock components into the nucleus, which is regulated in many cases by kinases. In mammals, the kinase promoting the nuclear import of the key clock component Period 2 (PER2) is unknown. Here, we show that the cyclin-dependent kinase 5...
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In: Trends in Neurosciences, 2018, vol. 41, no. 10, p. 677–688
The rotation of the Earth around its axis causes periodic exposure of half of its surface to sunlight. This daily recurring event has been internalized in most organisms in the form of cellular circadian clock mechanisms. These cellular clocks are synchronized with each other in various ways to establish circadian networks that build the circadian program in tissues and organs, coordinating...
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In: Brain Topography, 2010, vol. 23, no. 3, p. 311-320
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In: Journal of Molecular Evolution, 2003, vol. 57, p. S286-S289
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In: Journal of Scheduling, 2008, vol. 11, no. 2, p. 105-120
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In: Requirements Engineering, 2005, vol. 10, no. 3, p. 173-174
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