In: Physical Chemistry Chemical Physics, 2012, vol. 14, no. 8, p. 2929-2933
We present a series of experimental results that disclose the crucial role of ionic strength and partial volume fractions in the control of the phase behaviour of binary protein mixtures. Our findings can be understood as that the ionic strength determines the relative contribution of the entropy of the protein counter-ions to the overall thermodynamics of the system. Associative phase separation...
|
In: The Journal of Physical Chemistry B, 2010, vol. 114, p. 11875–11883
We report on the size, shape, structure, and interactions of lysozyme in the ternary system lysozyme/DMSO/water at low protein concentrations. Three structural regimes have been identified, which we term the “folded” (0 DMSO DMSO DMSO < 1.0) regime. Lysozyme resides in a...
|
In: Journal of Colloid and Interface Science, 2009, vol. 339, no. 2, p. 317-324
We describe the preparation and characterisation of inorganic–organic hybrid block copolymer silver nanoparticles via the preparation of spherical multi-responsive polymeric micelles of poly(N-methyl-2-vinyl pyridinium iodide)-block-poly(ethylene oxide), P2MVP₃₈-b-PEO₂₁₁ and poly(acrylic acid)-block-poly(isopropyl acrylamide),...
|
In: European Polymer Journal, 2009, vol. 45, no. 10, p. 2913-2925
The formation of spherical micelles in aqueous solutions of poly(N-methyl-2-vinyl pyridinium iodide)-block-poly(ethylene oxide), P2MVP-b-PEO and poly(acrylic acid)-block-poly(vinyl alcohol), PAA-b-PVOH has been investigated with light scattering-titrations, dynamic and static light scattering, and ¹H 2D Nuclear Overhauser Effect Spectroscopy. Complex coacervate...
|
In: Angewandte Chemie International Edition, 2010, vol. 49, no. 4, p. 708 - 711
Coassembly of an ABA triblock copolymer with charged end blocks and an oppositely charged polyelectrolyte yields gels that respond to changes in concentration, temperature, ionic strength, pH value, and charge composition. Above the critical gel concentration, the triblock copolymers bridge micelles, forming a sample-spanning transient network of interconnected micelles.
|
In: The European Physical Journal E, 2009, vol. 30, no. 4, p. 351-359
Light scattering and small-angle neutron scattering experiments were performed on comicelles of several combinations of oppositely charged (block co)polymers in aqueous solutions. Fundamental differences between the internal structure of this novel type of micelle --termed complex coacervate core micelle (C3Ms), polyion complex (PIC) micelle, block ionomer complex (BIC), or interpolyelectrolyte...
|