Refine my results

Resolving the fast kinetics of cooperative binding: Ca²⁺ buffering by calretinin

Faas, Guido C. ; Schwaller, Beat ; Vergara, Julio L. ; Mody, Istvan

In: PLoS Biology, 2007/5/11/e311 doi:10.1371/journal.pbio.0050311

Cooperativity is one of the most important properties of molecular interactions in biological systems. It is the ability to influence ligand binding at one site of a macromolecule by previous ligand binding at another site of the same molecule. As a consequence, the affinity of the macromolecule for the ligand is either decreased (negative cooperativity) or increased (positive cooperativity)....