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  • Stocker and Andreas S....
  • Thum Department of Biology, University of Fribourg, CH-1700 Fribourg, Switzerland ´ Correspondence to be sent to: Andreas S....
  • Gerber B, Stocker RF, Tanimura T, Thum AS. 2009....
  • Apostolopoulou , Annekathrin Widmann and Andreas S....
  • Thum 1 Department of Biology, University of Fribourg, 1700 Fribourg, Switzerland and 2Department of Biology, University of Konstanz, 78464 Konstanz, Germany Correspondence to be sent to: Andreas S....
  • von Essen AM, Pauls D, Thum AS, Sprecher SG. 2011....
Université de Fribourg

Four individually identified paired dopamine neurons signal reward in larval Drosophila

Rohwedder, Astrid ; Wenz, Nana L. ; Stehle, Bernhard ; Huser, Annina ; Yamagata, Nobuhiro ; Zlatic, Marta ; Truman, James W. ; Tanimoto, Hiromu ; Saumweber, Timo ; Gerber, Bertram ; Thum, Andreas S.

In: Current Biology, 2016, vol. 26, no. 5, p. 661–669

Dopaminergic neurons serve multiple functions, including reinforcement processing during associative learning [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12]. It is thus warranted to understand which dopaminergic neurons mediate which function. We study larval Drosophila, in which only approximately 120 of a total of 10,000 neurons are dopaminergic, as judged by the expression of tyrosine...

  • Truman,4 Hiromu Tanimoto,3 Timo Saumweber,5,* Bertram Gerber,5,6,7,* and Andreas S....
  • Selcho, M., Pauls, D., Han, K.A., Stocker, R.F., and Thum, A.S. (2009)....
  • Apostolopoulou, A.A., Mazija, L., Wust, A., and Thum, A.S. (2014)....
Université de Fribourg

Neuropeptide F neurons modulate sugar reward during associative olfactory learning of Drosophila larvae

Rohwedder, Astrid ; Selcho, Mareike ; Chassot, Bérénice ; Thum, Andreas S.

In: Journal of Comparative Neurology, 2015, vol. 523, no. 18, p. 2637–2664

All organisms continuously have to adapt their behavior according to changes in the environment in order to survive. Experience-driven changes in behavior are usually mediated and maintained by modifications in signaling within defined brain circuits. Given the simplicity of the larval brain of Drosophila and its experimental accessibility on the genetic and behavioral level, we analyzed if...

  • Neuropeptide F Neurons Modulate Sugar Reward During Associative Olfactory Learning of Drosophila Larvae Astrid Rohwedder,1 Mareike Selcho,2 Brnice Chassot,1 and Andreas S....
  • *CORRESPONDENCE TO: Andreas S....
  • Apostolopoulou AA, Mazija L, Wust A, Thum AS. 2014....
Université de Fribourg

Potency of transgenic effectors for neurogenetic manipulation in Drosophila larvae

Pauls, Dennis ; Essen, Alina von ; Lyutova, Radostina ; Giesen, Lena van ; Rosner, Ronny ; Wegener, Christian ; Sprecher, Simon G.

In: Genetics, 2014, vol. 199, no. 1, p. 25–37

Genetic manipulations of neuronal activity are a cornerstone of studies aimed to identify the functional impact of defined neurons for animal behavior. With its small nervous system, rapid life cycle, and genetic amenability, the fruit fly Drosophila melanogaster provides an attractive model system to study neuronal circuit function. In the past two decades, a large repertoire of elegant genetic...

  • Acknowledgments The authors thank Mareike Selcho, Konrad Öchsner, and Georg Nagel for technical assistance and/or comments on the article and Andreas Thum, Martin Schwärzel, Robert Kittel, and Georg Nagel for providing flies....
  • Thum, A....
  • Thum, and S....
Print Media
110 ans, 28000 éditions
Médiathèque Valais

Le Nouvelliste

Nouvelliste (Sion)

Sion : Nouvelliste valaisan, 1903

  • Aug 22, 2011: Andrea Salvisberg à 2’34. 59....
  • Nov 8, 2008: Les indications sont sur l l'Internet. ¦ • Parmi les rencontres, il y a le FC Vaduz,mais aussi la légende de : l'alpinisme de l'extrême Reinhold Andréas Messner....
  • Oct 21, 2008: Madame André MOK papa de M™ Andrée Barmaz, enseignante dans les classes de laVille de Sion....
  • See the 96 results in the newspaper "Le Nouvelliste"
Print Media
140 ans, 41000 éditions
Bibliothèque publique et universitaire

L'Impartial

La Chaux-de-Fonds : L'Impartial, 1880

No spécimen [0] (27.12.1880); no 1 (1.1.1881) -

  • Dec 22, 2014: Andre Myhrer (Su) à 3’’80....
  • Jul 6, 2013: Bien que nous ayons quelques réserves sur ce nouveau programme, je suis satisfait que le Président du Conseil exécutif bernois et directeur de l’Economie publique, Andreas Rickenbacher a embrayé dans le même sens: «Le Conseil fédéral se propose de promouvoir davantage l’innovation dans l’agriculture et la filière alimentaire, d’accroître la compétitivité et de soutenir d’une manière plus ciblée les prestations d’intérêt public.»...
  • Apr 26, 2013: «Chez nous, c’est l’euphorie», a surenchéri Andrea Bettiga....
  • See the 499 results in the newspaper "L'Impartial"
Université de Fribourg

Nutritional value–Dependent and nutritional value–Independent effects on Drosophila melanogaster larval behavior

Rohwedder, Astrid ; Pfitzenmaier, Johanna E. ; Ramsperger, Noel ; Apostolopoulou, Anthi A. ; Widmann, Annekathrin ; Thum, Andreas S.

In: Chemical Senses, 2012, vol. 37, no. 8, p. 711-721

Gustatory stimuli allow an organism not only to orient in its environment toward energy-rich food sources to maintain nutrition but also to avoid unpleasant or even poisonous substrates. For both mammals and insects, sugars—perceived as “sweet”—potentially predict nutritional benefit. Interestingly, even Drosophila adult flies are attracted to most high-potency sweeteners preferred by...

  • Apostolopoulou , Annekathrin Widmann and Andreas S....
  • Thum 1 Department of Biology, University of Fribourg, 1700 Fribourg, Switzerland and 2Department of Biology, University of Konstanz, 78464 Konstanz, Germany Correspondence to be sent to: Andreas S....
  • von Essen AM, Pauls D, Thum AS, Sprecher SG. 2011....
Université de Fribourg

Diversity, variability, and suboesophageal connectivity of antennal lobe neurons in D. melanogaster larvae

Thum, Andreas S. ; Leisibach, Basil ; Gendre, Nanaë ; Selcho, Mareike ; Stocker, Reinhard F.

In: The Journal of Comparative Neurology, 2011, vol. 59, no. 17, p. 3415–3432

Whereas the “vertical” elements of the insect olfactory pathway, the olfactory receptor neurons and the projection neurons, have been studied in great detail, local interneurons providing “horizontal” connections in the antennal lobe were ignored for a long time. Recent studies in adult Drosophila demonstrate diverse roles for these neurons in the integration of odor information,...

  • Thum,1* B....
  • *CORRESPONDENCE TO: Andreas S....
  • Gerber B, Stocker RF, Tanimura T, Thum AS. 2009....
Université de Fribourg

Electric shock-induced associative olfactory learning in Drosophila larvae

Pauls, Dennis ; Pfitzenmaier, Johanna E.R. ; Krebs-Wheaton, Rebecca ; Selcho, Mareike ; Stocker, Reinhard F. ; Thum, Andreas S.

In: Chemical Senses, 2010, vol. 35, no. 4, p. 335-346

Associative plasticity is a basic essential attribute of nervous systems. As shown by numerous reports, Drosophila is able to establish simple forms of appetitive and aversive olfactory associations at both larval and adult stages. Whereas most adult studies on aversive learning employed electric shock as a negative reinforcer, larval paradigms essentially utilized gustatory stimuli to...

  • Stocker and Andreas S....
  • Thum Department of Biology, University of Fribourg, CH-1700 Fribourg, Switzerland ´ Correspondence to be sent to: Andreas S....
  • Gerber B, Stocker RF, Tanimura T, Thum AS. 2009....