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Université de Fribourg

Lipid droplet biogenesis from specialized ER subdomains

Choudhary, Vineet ; Schneiter, Roger

In: Microbial Cell, 2020, vol. 7, no. 8, p. 218–221

Lipid droplets (LDs) are cellular compartments dedicated to the storage of metabolic energy in the form of neutral lipids, commonly known as “fat”. The biogenesis of LDs takes place in the endoplasmic reticulum (ER), but its spatial and temporal organization is poorly understood. How exactly sites of LD formation are selected and the succession of proteins and lipids needed to mediate...

  • Schneiter (2020) ER subdomains define sites of LD formation FIGURE 1: LD biogenesis in the ER....
  • OPEN ACCESS | www.microbialcell.com 221 COPYRIGHT © 2020 Choudhary and Schneiter....
  • Please cite this article as: Vineet Choudhary and Roger Schneiter (2020)....
Université de Fribourg

Localization and functional characterization of the pathogenesis-related proteins Rbe1p and Rbt4p in Candida albicans

Bantel, Annick ; Darwiche, Rabih ; Rupp, Steffen ; Schneiter, Roger ; Sohn, Kai

In: PLOS ONE, 2018, vol. 13, no. 8, p. e0201932

Members of the Cysteine-rich secretory protein, Antigen 5 and Pathogenesis-related 1 (CAP) protein superfamily are important virulence factors in fungi but remain poorly characterized on molecular level. Here, we investigate the cellular localization and molecular function of Rbe1p and Rbt4p, two CAP family members from the human pathogen Candida albicans. We unexpectedly found that Rbe1p...

  • Author Contributions Conceptualization: Roger Schneiter, Kai Sohn....
  • Supervision: Roger Schneiter, Kai Sohn....
  • Writing – review & editing: Yannick Bantel, Steffen Rupp, Roger Schneiter, Kai Sohn....
Consortium of Swiss Academic Libraries

The role of lipids in the biogenesis of integral membrane proteins

Schneiter, Roger ; Toulmay, Alexandre

In: Applied Microbiology and Biotechnology, 2007, vol. 73, no. 6, p. 1224-1232

  • Appl Microbiol Biotechnol (2007) 73:1224–1232 DOI 10.1007/s00253-006-0707-9 MINI-REVIEW The role of lipids in the biogenesis of integral membrane proteins Roger Schneiter & Alexandre Toulmay Received: 29 August 2006 / Revised: 3 October 2006 / Accepted: 4 October 2006 / Published online: 17 November 2006 # Springer-Verlag 2006 Abstract Most integral membrane proteins are cotranslationally inserted into the lipid bilayer....
  • Schneiter (*) : A....
  • Mol Biol Cell 12:4090–4102 Schneiter R (1999) Brave little yeast, please guide us to Thebes: sphingolipid function in S. cerevisiae....
Université de Fribourg

The function of yeast CAP family proteins in lipid export, mating, and pathogen defense

Darwiche, Rabih ; Atab, Ola El ; Cottier, Stéphanie ; Schneiter, Roger

In: FEBS Letters, 2018, vol. 592, no. 8, p. 1304–1311

In their natural habitat, yeast cells are constantly challenged by changing environmental conditions and a fierce competition for limiting resources. To thrive under such conditions, cells need to adapt and divide quickly, and be able to neutralize the toxic compounds secreted by their neighbors. Proteins like the pathogen‐related yeast, Pry proteins, which belong to the large CAP/SCP/TAPS ...

  • The function of yeast CAP family proteins in lipid export, mating, and pathogen defense  Rabih Darwiche, Ola El Atab, Stephanie Cottier and Roger Schneiter Division of Biochemistry, Department of Biology, University of Fribourg, Switzerland Correspondence R....
  • Mol Cell Probes 26, 54–59. 3 Schneiter R and Di Pietro A (2013) The CAP protein superfamily: function in sterol export and fungal virulence....
  • Darwiche R and Schneiter R (2016) Cholesterol-binding by the yeast CAP faimily member, Pry1, requires the presence of an aliphatic side chain on cholesterol....
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Université de Fribourg

Cholesterol-binding by the yeast CAP family member pry1 requires the presence of an aliphatic side chain on cholesterol

Darwiche, Rabih ; Schneiter, Roger

In: Journal of Steroids & Hormonal Science, 2016, vol. 2016, p. -

Pathogen-related yeast protein 1 (Pry1) is a Saccharomyces cerevisiae member of the CAP/SCP/TAPS superfamily. Although, CAP proteins have been proposed to be implicated in a number of physiological processes, such as pathogen virulence, sperm maturation and fertilization, host-pathogen interactions and defense mechanisms, the molecular mode of action of these proteins is poorly understood....

  • Journal of Steroids & Hormonal Science Darwiche and Schneiter, J Steroids Hormon Sci 2016, 7:2 http://dx.doi.org/10.4172/2157-7536.1000172 Short Communication Open Access Cholesterol-Binding by the Yeast CAP Family Member Pry1 Requires the Presence of an Aliphatic Side Chain on Cholesterol Rabih Darwiche and Roger Schneiter* University of Fribourg, Department of Biology, 1700 Fribourg, Switzerland *Corresponding author: Schneiter R, University of Fribourg, Department of Biology, Chemin du Musée 10, 1700 Fribourg, Switzerland, E-mail: roger.schneiter@unifr.ch Receiving date: Mar 01, 2016; Accepted date: May 02, 2016; Publishing date: May 07, 2016 Copyright: © 2016 Darwiche R, et al....
  • Schneiter R, Di-Pietro A (2013) The CAP protein superfamily: function in sterol export and fungal virulence....
  • Jacquier N, Schneiter R (2012) Mechanisms of sterol uptake and transport in yeast....
Print Media
75 ans, 18482 éditions
Bibliothèque de la ville de la Chaux-de-Fonds

La Sentinelle : quotidien socialiste

La Chaux de Fonds : [successivement] Union des sociétés ouvrières, Société d'Edition et de propagande socialiste, Parti ouvrier, Parti ouvrier suisse, Parti socialiste neuchâtelois et jurassien, "La Sentinelle"

Année 1, no 1 (4.1.1890) - année 76, no 224 (30.9.1965)

  • Sep 27, 1965: Nommé vicaire à G enève reçu samedi une délégation de la ï |_ > ] commune de La Chaux-de-Fonds con­ L ’abbé loclois Roger N oirjean a été duite p ar A ndré Sandoz....
  • Sep 21, 1965: Roger Frey Paris. — L’une des personnalités gaullistes les plus m arquantes, M....
  • Sep 18, 1965: Heinz Schneiter, demi, 12 avril 1935, employé de banque....
  • See the 497 results in the newspaper "La Sentinelle"
Université de Fribourg

The CAP protein superfamily: function in sterol export and fungal virulence

Schneiter, Roger ; Pietro, Antonio Di

In: BioMolecular Concepts, 2013, vol. 4, no. 5, p. 519-525

CAP superfamily proteins, also known as sperm-coating proteins, are found in all kingdoms of life and have been implicated in a variety of physiological contexts, including immune defense in plants and mammals, sperm maturation and fertilization, fungal virulence, and toxicity of insect and reptile venoms as well as prostate and brain cancer. CAP family members are mostly secreted...

  • Schneiter and A....
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Print Media
66 ans, 12000 éditions
Médiathèque Valais

Journal et feuille d'avis du Valais

Sion : [s.n.], 1903-1968

Année 1(1929)-année 30(1960)

Université de Fribourg

Saccharomyces cerevisiae, a model to study sterol uptake and transport in eukaryotes

Reiner, Sonja ; Micolod, Delphine ; Schneiter, Roger

In: Biochemical Society Transactions, 2005, vol. 33, no. 5, p. 1186-1188

The molecular mechanisms that govern intracellular transport of sterols in eukaryotic cells are only poorly understood. Saccharomyces cerevisiae is a facultative anaerobic organism that requires supplementation with unsaturated fatty acids and sterols to grow in the absence of oxygen, as the synthesis of these lipids requires molecular oxygen. The fact that yeast grows well under anaerobic...

  • Published in Biochemical Society Transactions 33: 1186–1188, 2005 Saccharomyces cerevisiae, a model to study sterol uptake and transport in eukaryotes Sonja Reiner1, Delphine Micolod2, and Roger Schneiter2* 1 2 Institute of Biochemistry, Graz University of Technology, 8010 Graz, Austria; Department of Medicine, Division of Biochemistry, University of Fribourg, 1700 Fribourg, Switzerland Running title: sterol uptake and transport in yeast Key words: cholesterol, anaerobiosis, respiration, membrane transport, ABC transporter, Saccharomyces cerevisiae *Corresponding author: Roger Schneiter, University of Fribourg, Department of Medicine, Division of Biochemistry, Chemin du Musée 5, CH-1700 Fribourg, Switzerland; Phone: +41 26 300 8654, Fax: +41 26 300 9735, Email: roger.schneiter@unifr.ch -2- Abstract The molecular mechanisms that govern intracellular transport of sterols in eukaryotic cells are only poorly understood....
  • L. (1996) Science 272, 13531356 32 Köffel, R., Tiwari, R., Falquet, L. and Schneiter, R. (2005) Mol....
  • Chem. 277, 36152-36160 42 Eisenkolb, M., Zenzmaier, C., Leitner, E. and Schneiter, R. (2002) Mol....