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Genetic dissection of neural circuit anatomy underlying feeding behavior in Drosophila: Distinct classes of hugin-expressing neurons

Bader, Rüdiger ; Colomb, Julien ; Pankratz, Bettina ; Schröck, Anne ; Stocker, Reinhard F. ; Pankratz, Michael J.

In: The Journal of Comparative Neurology, 2007, vol. 502, no. 5, p. 848 - 856

The hugin gene of Drosophila encodes a neuropeptide with homology to mammalian neuromedin U. The hugin-expressing neurons are localized exclusively to the subesophageal ganglion of the central nervous system and modulate feeding behavior in response to nutrient signals. These neurons send neurites to the protocerebrum, the ventral nerve cord, the ring gland, and the pharynx...