In: Journal of Medical Entomology, 2009, vol. 46, no. 6, p. 1464-1467
- .; other species collected were Culex (Culex)
torrentium (Martini) and An. plumbeus (Table 1)....
- Pagac., R....
|
In: Developmental Cell, 2017, vol. 41, no. 6, p. 591–604.e7
Cells convert excess energy into neutral lipids that are made in the endoplasmic reticulum (ER) bilayer. The lipids are then packaged into spherical or budded lipid droplets (LDs) covered by a phospholipid monolayer containing proteins. LDs play a key role in cellular energy metabolism and homeostasis. A key unanswered question in the life of LDs is how they bud off from the ER. Here, we...
- In storage conditions, nutrients are
transformed into neutral lipids (oils) such as triglycerides, sterol
esters, or squalene, which are packaged into organelles called
lipid droplets (LDs) (Martin and Parton, 2006)....
- Pagac, M., Cooper, D.E., Qi, Y., Lukmantara, I.E., Mak, H.Y., Wu, Z., Tian, Y.,
Liu, Z., Lei, M., and Du, X. (2016)....
- Martin, S., and Parton, R.G. (2006)....
|
In: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015, vol. 1851, no. 5, p. 629–640
Five yeast enzymes synthesizing various glycerophospholipids belong to the CDP-alcohol phosphatidyltransferase (CAPT) superfamily. They only share the so-called CAPT motif, which forms the active site of all these enzymes. Bioinformatic tools predict the CAPT motif of phosphatidylinositol synthase Pis1 as either ER luminal or cytosolic. To investigate the membrane topology of Pis1, unique...
- Martin Pagac and Cécile Knöpfli for the data in Fig. 6, Dr....
- Pagac, H.V. de la Mora, C....
- Pagac, H.M....
|
Print Media
66 ans, 12000 éditions
Sion : [s.n.], 1903-1968
Année 1(1929)-année 30(1960)
|
Print Media
140 ans, 41000 éditions
La Chaux-de-Fonds : L'Impartial, 1880
No spécimen [0] (27.12.1880); no 1 (1.1.1881) -
- Sep 25, 1906: Emile Pfenni ger, rue Léopold-Rohert 147. 6706-50-t-
A ouer P uur St-Martin pro-
J
1
1
jeune homme pour faire les commissions» entre ses heures d'école. — S'adresser à Mme Biolley, rue Numa-Droz 14-a. 16373-1 On demande le plus vite Qû p u a n f a OCl ïulHC. possible une servante pour un petit ménage. 1629S-1 S'adresser au bureau de I'I MPARTIAL ....
- See the 1 results in the newspaper "L'Impartial"
|
In: Biochemical Journal, 2013, p. -
Ypc1p and Ydc1p are alkaline ceramide hydrolases, which reside in the ER. Ypc1p can catalyze the reverse reaction, i.e. the condensation of free fatty acids with phytosphingosine or dihydrosphingosine and overexpression of YPC1 or YDC1 can provide enough ceramide synthesis as to rescue the viability of cells lacking the normal acyl-CoA-dependent ceramide synthases. To better understand the...
- Martin Pagac and Arlette Bochud for helpful discussions....
- Pagac, M., Vazquez, H....
- Pagac, M., de la Mora, H....
|
In: Molecular Biology, 2012, p. -
All glycerophospholipids are made from phosphatidic acid, which, according to the traditional view, is generated at the cytosolic surface of the ER. In yeast, phosphatidic acid is synthesized de novo by two acyl-CoA dependent acylation reactions. The first is catalyzed by one of the two homologous glycerol-3-phosphate acyltransferases Gpt2p/Gat1p and Sct1p/Gat2p, the second by one of the two...
- "
Topology of the microsomal glycerol-3-phosphate acyltransferase Gpt2p/Gat1p of Saccharomyces cerevisiae1
Martin Pagac1,2,3, Hector M....
- S1B)(Pagac et al., 2011)....
- Microsomes were analyzed using UBI-mal and PEG-mal as recently described (Pagac et al., 2011)....
|
Thèse de doctorat : Università della Svizzera italiana, 2012 ; 2012COM001.
Introduction: Promoting health and physical activity in the workplace is advocated by public health institutions across the globe. There is a need to find effective ways to understand the determinants of participation in physical activity in order to outline appropriate communication strategies to promote physical activity behaviour change in the workplace setting. E-mails and text messages...
- E., Martin, B....
- Martin, B....
- Martin, B....
|
In: Eukaryotic Cell, 2009, vol. 8, no. 3, p. 306-314
After glycosylphosphatidylinositols (GPIs) are added to GPI proteins of Saccharomyces cerevisiae, a fatty acid of the diacylglycerol moiety is exchanged for a C26:0 fatty acid through the subsequent actions of Per1 and Gup1. In most GPI anchors the thus modified diacylglycerol-based anchor is subsequently transformed into a ceramide-containing anchor, a reaction, which requires Cwh43. Here...
- Pagac, A....
- Martin-Yken H., A....
- Martin. 1997....
|
In: Molecular Microbiology, 2008, vol. 67, no. 1, p. 202-212
Glycosylphosphatidylinositol (GPI) lipids of Trypanosoma brucei undergo lipid remodelling, whereby longer fatty acids on the glycerol are replaced by myristate (C14:0). A similar process occurs on GPI proteins of Saccharomyces cerevisiae where Per1p first deacylates, Gup1p subsequently reacylates the anchor lipid, thus replacing a shorter fatty acid by C26:0. Heterologous expression...
- The Gup1 homologue of Trypanosoma brucei is a GPI glycosylphosphatidylinositol remodelase
Malika Jaquenoud,1 Martin Pagac,1 Aita Signorell,2 Mohammed Benghezal,1† Jennifer Jelk,2 Peter Bütikofer2 and Andreas Conzelmann1* 1 Department of Medicine/Biochemistry, University of Fribourg, Chemin du Musée 5, CH-1700, Switzerland. 2 Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, CH-3012 Bern, Switzerland....
- https://doc.rero.ch
11
SUPPLEMENTARY MATERIAL FOR THE ARTICLE
THE GUP1 HOMOLOGUE OF TRYPANOSOMA BRUCEI IS A GPI GLYCOSYLPHOSPHATIDYLINOSITOL REMODELASE
Malika Jaquenoud*, Martin Pagac*, Aita Signorell†, Mohammed Benghezal*‡, Jennifer Jelk†, Peter Bütikofer† and Andreas Conzelmann*
From the Department of Medicine/Biochemistry, University of Fribourg, Chemin du Musée 5, CH-1700, Switzerland*, and the Institute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, CH-3012 Bern, Switzerland†
‡
present address: Helicobacter Research Laboratory, Microbiology M502, University of, Western
Australia, QEII Medical Centre, Nedlands, Western Australia 6009 Corresponding author e-mail: andreas.conzelmann@unifr.ch
1
A
pHAGUP1 vector
gup1
pHAtbGUP1 pHAtcGUP1 pHAafGUP1 -HA 50 pHAafGUP1 -Gas1p -Wbp1p
75
B
pHAGUP1 BY4742
gup1
pHAtbGUP1 pHAtcGUP1
C
immature Gas1p in %
70 60 50 40 30 20 10 0
average
vector
BY4742 pHAGUP1 vector pHAtbGUP1 pHAtcGUP1 pHAafGUP1
p=0.03 p=0.0034
Supplemental Figure S1
Supplementary Fig....
|