Refine my results

Document type

Institution

Specific Collection

Language

Keyword

    Université de Fribourg

    The microcephaly-associated protein Wdr62/CG7337 is required to maintain centrosome asymmetry in Drosophila neuroblasts

    Nair, Anjana Ramdas ; Singh, Priyanka ; Garcia, David Salvador ; Rodriguez-Crespo, David ; Egger, Boris ; Cabernard, Clemens

    In: Cell Reports, 2016, vol. 14, no. 5, p. 1100–1113

    Centrosome asymmetry has been implicated in stem cell fate maintenance in both flies and vertebrates, but the underlying molecular mechanisms are incompletely understood. Here, we report that loss of CG7337, the fly ortholog of WDR62, compromises interphase centrosome asymmetry in fly neural stem cells (neuroblasts). Wdr62 maintains an active interphase microtubule-organizing center (MTOC) by...

    See also: similar author names
    1 Nair, R.
    1 Nair, Rajesh