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First report of an mcr-1-harboring Salmonella enterica subsp. enterica serotype 4,5,12:i:- strain isolated from blood of a patient in Switzerland

M.Carroll, Laura ; Zurfluh, Katrin ; Jang, Hyein ; Gopinath, Gopal ; Nüesch-Inderbinen, Magdalena ; Poirel, Laurent ; Nordmann, Patrice ; Stephan, Roger ; Guldimann, Claudia

In: International Journal of Antimicrobial Agents, 2018, vol. 52, no. 5, p. 740–741

Key features of mcr-1-bearing plasmids from Escherichia coli isolated from humans and food

Zurfluh, Katrin ; Nüesch-Inderbinen, Magdalena ; Klumpp, Jochen ; Poirel, Laurent ; Nordmann, Patrice ; Stephan, Roger

In: Antimicrobial Resistance & Infection Control, 2017, vol. 6, p. 91

Mcr-1-harboring Enterobacteriaceae are reported worldwide since their first discovery in 2015. However, a limited number of studies are available that compared full-length plasmid sequences of human and animal origins.

Screening for fecal carriage of MCR-producing Enterobacteriaceae in healthy humans and primary care patients

Zurfluh, Katrin ; Stephan, Roger ; Widmer, Andreas ; Poirel, Laurent ; Nordmann, Patrice ; Nüesch, Hans-Jakob ; Hächler, Herbert ; Nüesch-Inderbinen, Magdalena

In: Antimicrobial Resistance & Infection Control, 2017, vol. 6, p. 28

The objective of this study was to test the efficacy of an inhibitor of the New Delhi metallo-β- lactamase (NDM-1). Inhibiting expression of this type of antibiotic-resistance gene has the potential to restore antibiotic susceptibility in all bacteria carrying the gene.Methods: We have constructed a peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) that selectively inhibits...

Occurrence and features of chromosomally encoded carbapenemases in Gram-negative bacteria in farm animals sampled at slaughterhouse level

Zurfluh, Katrin ; Hindermann, D. ; Nüesch-Inderbinen, Magdalena ; Poirel, Laurent ; Nordmann, Patrice ; Stephan, Roger

In: Archives Suisses de Médecine Vétérinaire, 2016, vol. 158, no. 6, p. 457-460

Occurrence of the plasmid-borne mcr-1 colistin resistance gene in extended-spectrum-β-lactamase-producing Enterobacteriaceae in river water and imported vegetable samples in Switzerland

Zurfuh, Katrin ; Poirel, Laurent ; Nordmann, Patrice ; Nüesch-Inderbinen, Magdalena ; Hächler, Herbert ; Stephan, Roger

In: Antimicrobial Agents and Chemotherapy, 2016, vol. 60, no. 4, p. 2594–2595

Emergence of Escherichia coli producing OXA-48 β-lactamase in the community in Switzerland

Zurfluh, Katrin ; Nüesch-Inderbinen, Magdalena T ; Poirel, Laurent ; Nordmann, Patrice ; Hächler, Herbert ; Stephan, Roger

In: Antimicrobial Resistance and Infection Control, 2016, vol. 4, p. 9

The emergence and worldwide spread of carbapenemase-producing Enterobacteriaceae is of great concern to public health services. The aim of this study was to investigate the occurrence of carbapenemase-producing Enterobacteriaceae in the community in Switzerland.Findings: One thousand and eighty-six stool samples of healthy humans (staff members of a food-processing company which were screened...