Université de Fribourg

Genetic separation of Listeria monocytogenes causing central nervous system infections in animals

Aguilar-Bultet, Lisandra ; Nicholson, Pamela ; Rychener, Lorenz ; Dreyer, Margaux ; Goezel, Bulent ; Origgi, Francesco C. ; Oevermann, Anna ; Frey, Joachim ; Falquet, Laurent

In: Frontiers in Cellular and Infection Microbiology, 2018, vol. 8, p. -

Listeria monocytogenes is a foodborne pathogen that causes abortion, septicemia, gastroenteritis and central nervous system (CNS) infections in ruminants and humans. L. monocytogenes strains mainly belong to two distinct phylogenetic groups, named lineages I and II. In general, clinical cases in humans and animals, in particular CNS infections, are caused by lineage I strains, while most of...

Université de Fribourg

Clostridium chauvoei, an evolutionary dead-end pathogen

Rychener, Lorenz ; In-Albon, Saria ; Djordjevic, Steven P. ; Nicholson, Pamela ; Chowdhury, Piklu Roy ; Ziech, Rosangela E. ; Vargas, Agueda C. de ; Frey, Joachim ; Falquet, Laurent

In: Frontiers in Microbiology, 2017, vol. 8, p. -

Full genome sequences of 20 strains of Clostridium chauvoei, the etiological agent of blackleg of cattle and sheep, isolated from four different continents over a period of 64 years (1951–2015) were determined and analyzed. The study reveals that the genome of the species C. chauvoei is highly homogeneous compared to the closely related species C. perfringens, a widespread pathogen that...