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Enhanced tumour growth and impaired cellular antitumoural defence in hepatic colorectal carcinoma metastasis in rats after laparoscopy compared to open surgery

Inderbitzin, D. Th. ; Marti, G. R. ; Eichenberger, S. ; Hoogewoud, H.-M. ; Kraehenbuehl, L.

In: Annals of Surgical Oncology, 2008, vol. 15, no. 4, p. p

Background This study aims to assess postoperative hepatic growth of colorectal adenocarcinoma metastasis and peritumoural macrophage counts after laparoscopy in an experimental animal model. Methods Thirty male syngenic WAG/Rij rats were randomised into two surgical groups: laparoscopy (LS; n = 15) using CO₂ at 12 mmHg and laparotomy (LT; n = 15; negative control) during an...